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Deconvolution of Sustained Neural Activity From Large-Scale Calcium Imaging Data
Related publications (38)
Subcortical correlates of consciousness with human single neuron recordings
Olaf Blanke, Fosco Bernasconi, Nathan Quentin Faivre, Michael Eric Anthony Pereira
Subcortical brain structures such as the basal ganglia or the thalamus are involved in regulating motor and cognitive behavior. However, their contribution to perceptual consciousness is still unclear, due to the inherent difficulties of recording subcorti ...
2024Tissue clearing applications in memory engram research
Johannes Gräff, Kwok Yui Reymond Yip
A memory engram is thought to be the physical substrate of the memory trace within the brain, which is generally depicted as a neuronal ensemble activated by learning to fire together during encoding and retrieval. It has been postulated that engram cell e ...
FRONTIERS MEDIA SA2023Neuronal correlates of goal-directed sensorimotor transformation in sensory, motor and higher-order cortical areas
An important function of the brain is to interpret incoming sensory information from the outside world to guide adaptive behavior. Understanding how and where sensory information is transformed into motor commands in a context- and learning-dependent manne ...
EPFL2023Molecular reconstruction and simulation of the Neuron-Glia-Vasculature system
The outstanding information processing capacity of the brain relies on numerous molecular mechanisms. It is an extremely energy-expensive function, which involves specialization and collaboration of different cell types. A common framework to study the com ...
EPFL2023Neuroengineering of hallucinations through fMRI neurofeedback: Understanding and modulating neural dynamics for the control of hallucinations in health and disease
Herberto Dhanis Pedro De Barros Camacho
Recent years have seen considerable progress in understanding brain function, and in modulating it through real-time fMRI neurofeedback (NF). Inspired by these advances, paired with the unique possibility of inducing the clinically relevant Presence Halluc ...
EPFL2023Uncovering the neural encoding of behavior in the adult Drosophila motor system
One of the most important goals in neuroscience research has always been to understand how animals control their behavior. However, the long focus on the role of brain neurons in behavioral control might be missing the full story. In fact, brain-wide fluct ...
EPFL2022Does powder averaging remove dispersion bias in diffusion MRI diameter estimates within real 3D axonal architectures?
Marco Pizzolato, Tim Bjørn Dyrby
Noninvasive estimation of axon diameter with diffusion MRI holds the potential to investigate the dynamic properties of the brain network and pathology of neurodegenerative diseases. Recent studies use powder averaging to account for complex white matter a ...
ACADEMIC PRESS INC ELSEVIER SCIENCE2022Advanced metabolite mapping at ultra-high field using 1H-MRS, 1H-MRSI and macromolecules: applications in a rat model of type C hepatic encephalopathy
Magnetic Resonance Spectroscopy (MRS) is the only technique capable of measuring a large number of metabolites simultaneously in vivo. Ultra-high magnetic fields (UHF) combined with ultra-short echo time (TE) sequences allow the detection of high-quality 1 ...
EPFL2022A 16-Channel 60µW Neural Synchrony Processor for Multi-Mode Phase-Locked Neurostimulation
Mahsa Shoaran, Uisub Shin, Cong Ding, Laxmeesha Somappa
Measuring neural oscillatory synchrony facilitates our understanding of complex brain networks and the underlying pathological states. Altering the cross-regional synchrony-as a measure of brain network connectivity-via phase-locked deep brain stimulation ...
IEEE2022Development and applications of hyperpolarized 13C and 1H MR spectroscopy of cerebral metabolism at ultra-high field
This thesis is composed of four studies centered on investigating cerebral metabolism using magnetic resonance spectroscopy (MRS) of hyperpolarized and non-hyperpolarized compounds at ultra-high field.
In the first two chapters, we studied longitudinally t ...
EPFL2021