Publication

High-resolution cryo-EM structure of urease from the pathogen Yersinia enterocolitica

Related publications (39)

A new synthetic access to furo[3,2-f]chromene analogues of an antimycobacterial

From the structure of 3,3-dimethyl-3H-benzofuro[3,2-f][1]-benzopyran, a selective in vitro inhibitor of mycobacterial growth, we have undertaken a structure-activity relationship investigation. We wish to report here our results on the use of [2+3] cycload ...

2008

Dynamics of antibodies from cryo-electron tomography

Paolo De Los Rios, Francesco Piazza

The issue of protein dynamics and its implications in the biological function of proteins are arousing greater and greater interest in molecular biology. In cryo-electron tomography experiments one takes several snapshots of a given biological macromolecul ...

Elsevier2005

The central domain of the matrix protein of HIV-1: influence on protein structure and virus infectivity

Oliver Hantschel

The central region of the matrix protein p17 of HIV-1 is known to be essential during virus assembly. We substituted alanines for amino acid triplets in this region of p17 (amino acid residues 47 to 55: NPG LLE TSE). Introduction of the respective mutation ...

Walter de Gruyter2004

Quaternary structure, protein dynamics, and synaptic function of SAP97 controlled by L27 domain interactions

Hilal Lashuel

Single-particle electron microscopy (EM) combined with biochemical measurements revealed the molecular shape of SAP97 and a monomer-dimer transition that depended on the N-terminal L27 domain. Overexpression of SAP97 drove GluR1 to synapses, potentiated AM ...

Elsevier2004

First asymmetric synthesis of the cyclohexanone subunit of baconipyrones A and B. Revision of its structure

Pierre Vogel, Rosario Scopelliti, Maris Turks

An asymmetric synthesis of the 3,5-dihydroxycyclohexanone subunit of baconipyrones A and B, as well as that of the hydroxydiketone subunit of baconipyrones C and D ((-)-(4S,6S)-4,6-dimethyl-5-hydroxynonan-3,7-dione), is described. Key steps include sulfur ...

2004

Self-assembly of the hydrophobin SC3 proceeds via two structural intermediates

Horst Vogel

Hydrophobins self assemble into amphipathic films at hydrophobic-hydrophilic interfaces. These proteins are involved in a broad range of processes in fungal development. We have studied the conformational changes that accompany the self-assembly of the hyd ...

2002

The First Simple, Donor-Free Salt of the Sb(OTeF5)6- Anion: Synthesis, Structure, Characterization, and Thermochemistry of Cs[Sb(OTeF5)6]

Cs[Sb(OTeF5)6] was prepd. and its crystal structure detd. in space group P42/n, Rw = 0.051. [on SciFinder (R)] ...

2001

Domain structure of secretin PulD revealed by limited proteolysis and electron microscopy

Henning Paul-Julius Stahlberg, Andreas Engel

Secretins, a superfamily of multimeric outer membrane proteins, mediate the transport of large macromolecules across the outer membrane of Gramnegative bacteria. Limited proteolysis of secretin PulD from the Klebsiella oxytoca pullulanase secretion pathway ...

Wiley-Blackwell2000

Bâtiment urbain à usage convertible: tentative de prévention du problème des locaux commerciaux vides

Structure d'accueil. Réversibilité bureaux-logements et logements-bureaux avec un minimum de moyens. ...

2000

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