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Fully automated detection, segmentation, and analysis of in vivo RPE single cells

Related publications (35)

Evidence for the two-body charmless baryonic decay B+ -> p(Lambda)over-bar

Jian Wang, Olivier Schneider, Yiming Li, Yi Zhang, Aurelio Bay, Guido Haefeli, Christoph Frei, Frédéric Blanc, Tatsuya Nakada, Michel De Cian, Luca Pescatore, François Fleuret, Elena Graverini, Chitsanu Khurewathanakul, Renato Quagliani, Maria Vieites Diaz, Federico Betti, Aravindhan Venkateswaran, Luis Miguel Garcia Martin, Katharina Müller, Zhirui Xu, Lei Zhang, Jessica Prisciandaro, Mark Tobin, Minh Tâm Tran, Niko Neufeld, Matthew Needham, Marc-Olivier Bettler, Greig Alan Cowan, Maurizio Martinelli, Donal Patrick Hill, Cédric Potterat, Liang Sun, Pietro Marino, Mirco Dorigo, Jean Wicht, Xiaoxue Han, Sebastiana Gianì, Liupan An, Federico Leo Redi, Ilya Komarov, Thibaud Humair, Maxime Schubiger, Hang Yin, Guido Andreassi, Violaine Bellée, Olivier Göran Girard, Axel Kuonen, Preema Rennee Pais, Pavol Stefko, Hans Dijkstra, Gerhard Raven, Peter Clarke, Frédéric Teubert, Giovanni Carboni, Victor Coco, Adam Davis, Paolo Durante, Yu Zheng, Anton Petrov, Maxim Borisyak, Feng Jiang

A search for the rare two-body charmless baryonic decay B+ -> p (Lambda) over bar is performed with pp collision data, corresponding to an integrated luminosity of 3 fb(-1), collected by the LHCb experiment at centre-of-mass energies of 7 and 8 TeV. An exc ...

Springer Science and Business Media LLC2017

Characterization of a Polymer-Based, Fully Organic Prosthesis for Implantation into the Subretinal Space of the Rat

Diego Ghezzi

Replacement strategies arise as promising approaches in case of inherited retinal dystrophies leading to blindness. A fully organic retinal prosthesis made of conjugated polymers layered onto a silk fibroin substrate is engineered. First, the biophysical a ...

Wiley-VCH Verlag2016

Gene therapy and bioengineering for retinal diseases: what is the future?

Diego Ghezzi

Sight restoration after retinal degeneration still represents an unmet goal. Since therapeutic strategies increasingly require interdisciplinary competencies, photoreceptor degeneration is attracting several research areas, including: life science, materia ...

2015

A Study of Yield Predictions for a Model of Homogeneous Self-Assembling Components

Massimo Mastrangeli

Self-assembly of homogeneous components has the advantage of being a decentralised and highly parallel method for assembling multiple target structures, and is ideal for effective large-scale manufacturing. Yet assembly yield may be negatively affected by ...

2015

A polymer-based interface restores light sensitivity in blind rats

Diego Ghezzi

Progressive degeneration of photoreceptors is one of the major causes of adult blindness in “industrialized” countries; as an example, Retinitis pigmentosa defines a set of monogenic hereditary retinal diseases, with a prevalence of 1:4000 worldwide, cause ...

2014

Novel ADAM9 homozygous mutation in a consanguineous Egyptian family with severe cone-rod dystrophy and cataract

Tatiana Favez

Objective To genetically and phenotypically describe a new ADAM9 homozygous mutation in a consanguineous family from Egypt with autosomal recessive cone-rod dystrophy (arCRD), anterior polar and posterior subcapsular cataract. Design, setting and participa ...

Bmj Publishing Group2014

A polymer-based interface restores light sensitivity in blind rats

Diego Ghezzi

Purpose: Sight restoration is one of the new frontiers for prosthetic devices that enable the electrical stimulation of neurons. In particular, diseases affecting the retinal pigment epithelium and photoreceptors but preserve the inner retinal layers are p ...

2014

Retinal pigment epithelium protein of 65 kDA gene-linked retinal degeneration is not modulated by chicken acidic leucine-rich epidermal growth factor-like domain containing brain protein/Neuroglycan C/chondroitin sulfate proteoglycan 5

Pascal Escher

Purpose: To analyze in vivo the function of chicken acidic leucine-rich epidermal growth factor-like domain containing brain protein/Neuroglycan C (gene symbol: Cspg5) during retinal degeneration in the Rpe65(-/-) mouse model of Leber congenital amaurosis. ...

Molecular Vision2013

A polymer-based interface restores light sensitivity in rat blind retinas

Diego Ghezzi

Purpose: Sight restoration is one of the new frontiers for prosthetic devices that enable the electrical stimulation of neurons. In particular, diseases that affect the retinal pigment epithelium and photoreceptors but preserve the inner retinal layers are ...

2013

A polymer-based interface restores light sensitivity in rat blind retinas

Diego Ghezzi

Sight restoration is one of the new frontiers for prosthetic devices that enable the electrical stimulation of neurons. In particular, diseases that affect the retinal pigment epithelium and photoreceptors but preserve the inner retinal layers are preferen ...

2013

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