Patient-reported outcomeA patient-reported outcome (PRO) is a health outcome directly reported by the patient who experienced it. It stands in contrast to an outcome reported by someone else, such as a physician-reported outcome, a nurse-reported outcome, and so on. PRO methods, such as questionnaires, are used in clinical trials or other clinical settings, to help better understand a treatment's efficacy or effectiveness. The use of digitized PROs, or electronic patient-reported outcomes (ePROs), is on the rise in today's health research setting.
Calcium pyrophosphate dihydrate crystal deposition diseaseCalcium pyrophosphate dihydrate (CPPD) crystal deposition disease, also known as pseudogout and pyrophosphate arthropathy, is a rheumatologic disease which is thought to be secondary to abnormal accumulation of calcium pyrophosphate dihydrate crystals within joint soft tissues. The knee joint is most commonly affected. The disease is metabolic in origin and its treatment remains symptomatic. CPPD has also been classified as an Autoimmune Paraneoplastic Manifestation of Myelodysplastic Syndrome.
Protocol (science)In natural and social science research, a protocol is most commonly a predefined procedural method in the design and implementation of an experiment. Protocols are written whenever it is desirable to standardize a laboratory method to ensure successful replication of results by others in the same laboratory or by other laboratories. Additionally, and by extension, protocols have the advantage of facilitating the assessment of experimental results through peer review.
Joint replacementReplacement arthroplasty (from Greek arthron, joint, limb, articulate, + plassein, to form, mould, forge, feign, make an image of), or joint replacement surgery, is a procedure of orthopedic surgery in which an arthritic or dysfunctional joint surface is replaced with an orthopedic prosthesis. Joint replacement is considered as a treatment when severe joint pain or dysfunction is not alleviated by less-invasive therapies. It is a form of arthroplasty, and is often indicated from various joint diseases, including osteoarthritis and rheumatoid arthritis.
OrthoticsOrthotics (Ορθός) is a medical specialty that focuses on the design and application of orthoses, or braces. An is "an externally applied device used to influence the structural and functional characteristics of the neuromuscular and skeletal systems." Orthotists are professionals who specialize in designing these braces. Orthotic devices are classified into four areas of the body according to the international classification system (ICS): orthotics of the lower extremities, orthotics of the upper extremities, orthotics for the trunk, and orthotics for the head.
Horse gaitHorses can use various gaits (patterns of leg movement) during locomotion across solid ground, either naturally or as a result of specialized training by humans. Terrestrial locomotion and Gait Gaits are typically categorized into two groups: the "natural" gaits that most horses will use without special training, and the "ambling" gaits that are various smooth-riding four-beat footfall patterns that may appear naturally in some individuals. Special training is often required before a horse will perform an ambling gait in response to a rider's command.
Gait abnormalityGait abnormality is a deviation from normal walking (gait). Watching a patient walk is an important part of the neurological examination. Normal gait requires that many systems, including strength, sensation and coordination, function in an integrated fashion. Many common problems in the nervous system and musculoskeletal system will show up in the way a person walks. Patients with musculoskeletal pain, weakness or limited range of motion often present conditions such as Trendelenburg's sign, limping, myopathic gait and antalgic gait.
Balance (ability)Balance in biomechanics, is an ability to maintain the line of gravity (vertical line from centre of mass) of a body within the base of support with minimal postural sway. Sway is the horizontal movement of the centre of gravity even when a person is standing still. A certain amount of sway is essential and inevitable due to small perturbations within the body (e.g., breathing, shifting body weight from one foot to the other or from forefoot to rearfoot) or from external triggers (e.g., visual distortions, floor translations).
QuestionA question is an utterance which serves as a request for information. Questions are sometimes distinguished from interrogatives, which are the grammatical forms typically used to express them. Rhetorical questions, for instance, are interrogative in form but may not be considered bona fide questions, as they are not expected to be answered. Questions come in a number of varieties. Polar questions are those such as the English example "Is this a polar question?", which can be answered with "yes" or "no".
Yes–no questionIn linguistics, a yes–no question, also known as a binary question, a polar question, or a general question, is a question whose expected answer is one of two choices, one that provides an affirmative answer to the question versus one that provides a negative answer to the question. Typically, in English, the choices are either "yes" or "no". Yes–no questions present an exclusive disjunction, namely a pair of alternatives of which only one is a felicitous answer.
