Phage therapyPhage therapy, viral phage therapy, or phagotherapy is the therapeutic use of bacteriophages for the treatment of pathogenic bacterial infections. This therapeutic approach emerged at the beginning of the 20th century but was progressively replaced by the use of antibiotics in most parts of the world after the Second World War. Bacteriophages, known as phages, are a form of virus that attach to bacterial cells and inject their genome into the cell.
Prior probabilityA prior probability distribution of an uncertain quantity, often simply called the prior, is its assumed probability distribution before some evidence is taken into account. For example, the prior could be the probability distribution representing the relative proportions of voters who will vote for a particular politician in a future election. The unknown quantity may be a parameter of the model or a latent variable rather than an observable variable.
Evolutionary pressureAny cause that reduces or increases reproductive success in a portion of a population potentially exerts evolutionary pressure, selective pressure or selection pressure, driving natural selection. It is a quantitative description of the amount of change occurring in processes investigated by evolutionary biology, but the formal concept is often extended to other areas of research. In population genetics, selective pressure is usually expressed as a selection coefficient.
Human extinctionHuman extinction is the hypothetical end of the human species due to either natural causes such as population decline from sub-replacement fertility, an asteroid impact, large-scale volcanism, or via anthropogenic destruction (self-extinction). For the latter, some of the many possible contributors include climate change, global nuclear annihilation, biological warfare, and ecological collapse. Other scenarios center on emerging technologies, such as advanced artificial intelligence, biotechnology, or self-replicating nanobots.
Background extinction rateBackground extinction rate, also known as the normal extinction rate, refers to the standard rate of extinction in Earth's geological and biological history before humans became a primary contributor to extinctions. This is primarily the pre-human extinction rates during periods in between major extinction events. Extinctions are a normal part of the evolutionary process, and the background extinction rate is a measurement of "how often" they naturally occur.
Extinction RebellionExtinction Rebellion (abbreviated as XR) is a UK-headquartered global environmental movement, with the stated aim of using nonviolent civil disobedience to compel government action to avoid tipping points in the climate system, biodiversity loss, and the risk of social and ecological collapse. Extinction Rebellion was established in Stroud in May 2018 by Gail Bradbrook, Simon Bramwell, and Roger Hallam, along with eight other co-founders from the campaign group Rising Up! Its first major action was to occupy the London Greenpeace offices on 17 October 2018, which was followed by the public launch at the "Declaration of Rebellion" on 31 October 2018 outside the UK Parliament.
