Synthetic biologySynthetic biology (SynBio) is a multidisciplinary field of science that focuses on living systems and organisms, and it applies engineering principles to develop new biological parts, devices, and systems or to redesign existing systems found in nature. It is a branch of science that encompasses a broad range of methodologies from various disciplines, such as biotechnology, biomaterials, material science/engineering, genetic engineering, molecular biology, molecular engineering, systems biology, membrane science, biophysics, chemical and biological engineering, electrical and computer engineering, control engineering and evolutionary biology.
Bayesian hierarchical modelingBayesian hierarchical modelling is a statistical model written in multiple levels (hierarchical form) that estimates the parameters of the posterior distribution using the Bayesian method. The sub-models combine to form the hierarchical model, and Bayes' theorem is used to integrate them with the observed data and account for all the uncertainty that is present. The result of this integration is the posterior distribution, also known as the updated probability estimate, as additional evidence on the prior distribution is acquired.
Natural exponential familyIn probability and statistics, a natural exponential family (NEF) is a class of probability distributions that is a special case of an exponential family (EF). The natural exponential families (NEF) are a subset of the exponential families. A NEF is an exponential family in which the natural parameter η and the natural statistic T(x) are both the identity. A distribution in an exponential family with parameter θ can be written with probability density function (PDF) where and are known functions.