Naturalistic spatiotemporal modulation of epiretinal stimulation increases the response persistence of retinal ganglion cell
Related publications (56)
Graph Chatbot
Chat with Graph Search
Ask any question about EPFL courses, lectures, exercises, research, news, etc. or try the example questions below.
DISCLAIMER: The Graph Chatbot is not programmed to provide explicit or categorical answers to your questions. Rather, it transforms your questions into API requests that are distributed across the various IT services officially administered by EPFL. Its purpose is solely to collect and recommend relevant references to content that you can explore to help you answer your questions.
Retinal prostheses are being developed to restore vision in blind patients with photoreceptor degeneration. Electrodes arrays were subretinally implanted in transgenic P23H rats with their photoreceptors degenerated. Electrical stability of the implants wa ...
The retina is one of the best known quantum detectors with rods able to reliably respond to single photons. However, estimates on the number of photons eliciting conscious perception, based on signal detection theory, are systematically above these values ...
Since 2002, when the first reports on the discovery of a novel type of mammalian ocular photoreceptor were published, a new field of study at the intersection of photobiology and architecture started to emerge. These novel non-rod, non-cone photoreceptors ...
Congenital stationary night blindness (CSNB) is a heterogeneous retinal disorder characterized by visual impairment under low light conditions. This disorder is due to a signal transmission defect from rod photoreceptors to adjacent bipolar cells in the re ...
Interfacing organic electronics and biology offers new possibilities in biotechnology, due to the unique properties exhibited by organic conducting polymers (e.g. biological affinity, mechanical flexibility, ease of functionalization and cost effectiveness ...
Ocular development is controlled by a complex network of transcription factors, cell cycle regulators, and diffusible signaling molecules. Together, these molecules regulate cell proliferation, apoptosis and specify retinal fate. In the zebrafish (Danio re ...
Interfacing organic electronics and biology offers new possibilities in biotechnology, due to the unique properties exhibited by organic conducting polymers (e.g. biological affinity, mechanical flexibility, ease of functionalization and cost effectiveness ...
RPE65-related Leber's congenital amaurosis (LCA) is a rod-cone dystrophy whose clinical outcome is mainly attributed to the loss of rod photoreceptors followed by cone degeneration. Pathogenesis in Rpe65-/- mice is characterized by a slow and progressive d ...
Interfacing organic electronics and biology offers new possibilities in biotechnology, due to the unique properties exhibited by organic conducting polymers (e.g. biological affinity, mechanical flexibility and ease of functionalization). OCP have been exp ...
We present a finite element based simulation and analysis method to describe the spatial extent of stimulation and the effects of electrode–tissue interactions in subretinal prostheses. In particular, we estimate the threshold stimulation current needed to ...