Suprachiasmatic nucleusThe suprachiasmatic nucleus or nuclei (SCN) is a small region of the brain in the hypothalamus, situated directly above the optic chiasm. It is the principal circadian pacemaker in mammals and is necessary for generating circadian rhythms. Reception of light inputs from photosensitive retinal ganglion cells allow the SCN to coordinate the subordinate cellular clocks of the body and entrain to the environment. The neuronal and hormonal activities it generates regulate many different body functions in an approximately 24-hour cycle.
CLOCKCLOCK (from circadian locomotor output cycles kaput) is a gene encoding a basic helix-loop-helix-PAS transcription factor that is known to affect both the persistence and period of circadian rhythms. Research shows that the gene plays a major role as an activator of downstream elements in the pathway critical to the generation of circadian rhythms. The CLOCK gene was first identified in 1997 by Joseph Takahashi and his colleagues.
SpectrumA spectrum (: spectra or spectrums) is a condition that is not limited to a specific set of values but can vary, without gaps, across a continuum. The word was first used scientifically in optics to describe the rainbow of colors in visible light after passing through a prism. As scientific understanding of light advanced, it came to apply to the entire electromagnetic spectrum. It thereby became a mapping of a range of magnitudes (wavelengths) to a range of qualities, which are the perceived "colors of the rainbow" and other properties which correspond to wavelengths that lie outside of the visible light spectrum.
Laboratory for Laser EnergeticsThe Laboratory for Laser Energetics (LLE) is a scientific research facility which is part of the University of Rochester's south campus, located in Brighton, New York. The lab was established in 1970 with operations jointly funded by the United States Department of Energy, the University of Rochester and the New York State government. The Laser Lab was commissioned to investigate high-energy physics involving the interaction of extremely intense laser radiation with matter.
NarcolepsyNarcolepsy is a chronic neurological disorder that involves a decreased ability to regulate sleep–wake cycles. Symptoms often include periods of excessive daytime sleepiness and brief involuntary sleep episodes. About 70% of those affected also experience episodes of sudden loss of muscle strength, known as cataplexy. Narcolepsy paired with cataplexy is evidenced to be an autoimmune disorder. These experiences of cataplexy can be brought on by strong emotions.
DaytimeDaytime as observed on Earth is the period of the day during which a given location experiences natural illumination from direct sunlight. Daytime occurs when the Sun appears above the local horizon, that is, anywhere on the globe's hemisphere facing the Sun. In direct sunlight the movement of the sun can be recorded and observed using a sundial that casts a shadow that slowly moves during the day. Other planets and natural satellites that rotate relative to a luminous primary body, such as a local star, also experience daytime, but this article primarily discusses daytime on Earth.
Idiopathic hypersomniaIdiopathic hypersomnia (IH) is a neurological disorder which is characterized primarily by excessive sleep and excessive daytime sleepiness (EDS). The condition typically becomes evident in early adulthood and most patients diagnosed with IH will have had the disorder for many years prior to their diagnosis. , an FDA-approved medication exists for IH called Xywav, which is oral solution of calcium, magnesium, potassium, and sodium oxybates; in addition to several off-label treatments (primarily FDA-approved narcolepsy medications).
Open worldIn video games, an open world is a virtual world in which the player can approach objectives freely, as opposed to a world with more linear and structured gameplay. Notable games in this category include The Legend of Zelda (1986), Grand Theft Auto III (2001) and Minecraft (2011). Games with open or free-roaming worlds typically lack level structures like walls and locked doors, or the invisible walls in more open areas that prevent the player from venturing beyond them; only at the bounds of an open-world game will players be limited by geographic features like vast oceans or impassable mountains.
Realism (arts)Realism in the arts is generally the attempt to represent subject matter truthfully, without artificiality and avoiding speculative and supernatural elements. The term is often used interchangeably with naturalism, although these terms are not synonymous. Naturalism, as an idea relating to visual representation in Western art, seeks to depict objects with the least possible amount of distortion and is tied to the development of linear perspective and illusionism in Renaissance Europe.
Mathematics and artMathematics and art are related in a variety of ways. Mathematics has itself been described as an art motivated by beauty. Mathematics can be discerned in arts such as music, dance, painting, architecture, sculpture, and textiles. This article focuses, however, on mathematics in the visual arts. Mathematics and art have a long historical relationship. Artists have used mathematics since the 4th century BC when the Greek sculptor Polykleitos wrote his Canon, prescribing proportions conjectured to have been based on the ratio 1: for the ideal male nude.
