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Organohalide respiration in Firmicutes: energy metabolism and transcription regulation

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Adaptive Response of Group B Streptococcus to High Glucose Conditions: New Insights on the CovRS Regulation Network

Isabella Santi

Although the contribution of carbohydrate catabolism to bacterial colonization and infection is well recognized, the transcriptional changes during these processes are still unknown. In this study, we have performed comparative global gene expression analy ...

Public Library of Science2013

Reactive oxygen species production and signalling as a component of salinity tolerance mechanism in cereals

Amandine Massart

Reactive Oxygen Species (ROS) are highly reactive and toxic by-products of the aerobic metabolism, which are overproduced during period of stress. They disturb the cell machinery and induce oxidative damages on important biological macromolecules. Salinity ...

2013

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Corrinoids (derivatives of vitamin B12) are an essential cofactor of reductive dehalogenases, the key enzymes involved in the environmental-friendly process of organohalide respiration (OHR). However, genomic and physiological analyses of obligate OHR bact ...

2013

Corrinoid auxotrophy in the obligate organohalide-respiring Dehalobacter restrictus

Christof Holliger, Aamani Rupakula Boyanapalli

2013

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Organohalide respiration (OHR) is a bacterial anaerobic respiratory metabolism dedicated to use halogenated compounds as terminal electron acceptors. OHR bacteria are strictly anaerobic microorganisms which use reductive dehalogenases (RdhA) as key enzymes ...

2012

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Desulfitobacterium spp. are ubiquitous organisms with a broad metabolic versatility and some isolates have the ability to use tetrachloroethene (PCE) as terminal electron acceptor. In order to identify proteins involved in this organohalide respiration pro ...

American Society for Microbiology2011

The Secret Life of NAD+: An Old Metabolite Controlling New Metabolic Signaling Pathways

Johan Auwerx, Carlos Canto Alvarez, Richardus Houtkooper

A century after the identification of a coenzymatic activity for NAD(+), NAD(+) metabolism has come into the spotlight again due to the potential therapeutic relevance of a set of enzymes whose activity is tightly regulated by the balance between the oxidi ...

Endocrine Society2010

Survey of one-carbon metabolism in Desulfitobacteria

Christof Holliger, Julien Maillard, Laure Prat

Desulfitobacterium is a Gram-positive obligate anaerobic bacterium affiliated to the Firmicutes with a highly versatile carbon and energy metabolism. Increasing interest in this genus came with its involvement in the degradation of chlorinated compounds us ...

2010

Heritable changes to the transcriptome that are independent to changes in the genome are defined as epigenetics. DNA methylation and posttranslational modifications of histones, such as acetylation/deacetylation and methylation/demethylation of lysine resi ...

Elsevier2010

GENETIC INSTABILITY OF THE DEHALORESPIRATION PROCESS IN DESULFITOBACTERIUM HAFNIENSE STRAIN TCE1

Christof Holliger, Julien Maillard, Aurélie Duret

Dehalorespiration is an environmental-friendly bacterial anaerobic respiration that couples reductive dechlorination of chlorinated organic pollutants with energy conservation. Tetrachloroethene (PCE) respiration is encoded by the pce gene cluster in Desul ...

2010