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Fitting summary statistics of neural data with a differentiable spiking network simulator

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Single-unit recording

In neuroscience, single-unit recordings (also, single-neuron recordings) provide a method of measuring the electro-physiological responses of a single neuron using a microelectrode system. When a neuron generates an action potential, the signal propagates down the neuron as a current which flows in and out of the cell through excitable membrane regions in the soma and axon. A microelectrode is inserted into the brain, where it can record the rate of change in voltage with respect to time.

Feedforward neural network

A feedforward neural network (FNN) is one of the two broad types of artificial neural network, characterized by direction of the flow of information between its layers. Its flow is uni-directional, meaning that the information in the model flows in only one direction—forward—from the input nodes, through the hidden nodes (if any) and to the output nodes, without any cycles or loops, in contrast to recurrent neural networks, which have a bi-directional flow.

Descriptive statistics

A descriptive statistic (in the count noun sense) is a summary statistic that quantitatively describes or summarizes features from a collection of information, while descriptive statistics (in the mass noun sense) is the process of using and analysing those statistics. Descriptive statistics is distinguished from inferential statistics (or inductive statistics) by its aim to summarize a sample, rather than use the data to learn about the population that the sample of data is thought to represent.

Likelihood principle

In statistics, the likelihood principle is the proposition that, given a statistical model, all the evidence in a sample relevant to model parameters is contained in the likelihood function. A likelihood function arises from a probability density function considered as a function of its distributional parameterization argument.

Quasi-likelihood

In statistics, quasi-likelihood methods are used to estimate parameters in a statistical model when exact likelihood methods, for example maximum likelihood estimation, are computationally infeasible. Due to the wrong likelihood being used, quasi-likelihood estimators lose asymptotic efficiency compared to, e.g., maximum likelihood estimators. Under broadly applicable conditions, quasi-likelihood estimators are consistent and asymptotically normal. The asymptotic covariance matrix can be obtained using the so-called sandwich estimator.

Bayesian statistics

Bayesian statistics (ˈbeɪziən or ˈbeɪʒən ) is a theory in the field of statistics based on the Bayesian interpretation of probability where probability expresses a degree of belief in an event. The degree of belief may be based on prior knowledge about the event, such as the results of previous experiments, or on personal beliefs about the event. This differs from a number of other interpretations of probability, such as the frequentist interpretation that views probability as the limit of the relative frequency of an event after many trials.

Relative likelihood

In statistics, when selecting a statistical model for given data, the relative likelihood compares the relative plausibilities of different candidate models or of different values of a parameter of a single model. Assume that we are given some data x for which we have a statistical model with parameter θ. Suppose that the maximum likelihood estimate for θ is . Relative plausibilities of other θ values may be found by comparing the likelihoods of those other values with the likelihood of .

Brain

A brain is an organ that serves as the center of the nervous system in all vertebrate and most invertebrate animals. It is located in the head, usually close to the sensory organs for senses such as vision. It is the most complex organ in a vertebrate's body. In a human, the cerebral cortex contains approximately 14–16 billion neurons, and the estimated number of neurons in the cerebellum is 55–70 billion. Each neuron is connected by synapses to several thousand other neurons.

Neurotransmission

Neurotransmission (Latin: transmissio "passage, crossing" from transmittere "send, let through") is the process by which signaling molecules called neurotransmitters are released by the axon terminal of a neuron (the presynaptic neuron), and bind to and react with the receptors on the dendrites of another neuron (the postsynaptic neuron) a short distance away. A similar process occurs in retrograde neurotransmission, where the dendrites of the postsynaptic neuron release retrograde neurotransmitters (e.g.

Activity recognition

Activity recognition aims to recognize the actions and goals of one or more agents from a series of observations on the agents' actions and the environmental conditions. Since the 1980s, this research field has captured the attention of several computer science communities due to its strength in providing personalized support for many different applications and its connection to many different fields of study such as medicine, human-computer interaction, or sociology.