Publication
Inferring Transmission Fitness Advantage of SARS-CoV-2 Variants of Concern in Wastewater Using Digital PCR
Related publications (103)
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High-throughput transcriptomics is of increasing fundamental biological and clinical interest. The generation of molecular data from large collections of samples, such as biobanks and drug libraries, is boosting the development of new biomarkers and treatm ...
Dordrecht2024Comparison of Three Viral Nucleic Acid Preamplification Pipelines for Sewage Viral Metagenomics
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Viral metagenomics is a useful tool for detecting multiple human viruses in urban sewage. However, more refined protocols are required for its effective use in disease surveillance. In this study, we investigated the performance of three different preampli ...
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Advances in nanopore technology and data processing have rendered DNA sequencing highly accessible, unlocking a new realm of biotechnological opportunities. Commercially available nanopores for DNA sequencing are of biological origin and have certain disad ...
Springer Link2024Benchmarking informatics approaches for virus discovery: caution is needed when combining in silico identification methods
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Washington2024Optimised set of oligonucleotides for bulk rna barcoding and sequencing
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The present invention relates generally to the field of nucleic acid sequencing and provides oligonucleotide molecules and barcodes contained therein. These oligonucleotide molecules and barcodes molecules are useful in sequencing to identify and resolve e ...
2023Systematic benchmarking of single-cell ATAC-sequencing protocols
Bart Deplancke, Jörn Pezoldt, Camille Lucie Germaine Lambert
Benchmarking of scATAC-seq protocols demonstrates the effects of data quality on downstream analyses. Single-cell assay for transposase-accessible chromatin by sequencing (scATAC-seq) has emerged as a powerful tool for dissecting regulatory landscapes and ...
NATURE PORTFOLIO2023Construction of sequencing libraries from a ribonucleic acid (rna) using tailing and ligation of cdna (tlc)
The present invention provides a method for preparing a sequencing library from a ribonucleic acid (RNA) sample. ...
2023A Biallelic Truncating Variant in the TPR Domain of GEMIN5 Associated with Intellectual Disability and Cerebral Atrophy
GEMIN5 is a multifunctional RNA-binding protein required for the assembly of survival motor neurons. Several bi-allelic truncating and missense variants in this gene are reported to cause a neurodevelopmental disorder characterized by cerebellar atrophy, i ...
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Nanopore-based scanning system including a probe structure comprising a nanopore; suction means configured to draw an end of a (bio)molecule inside the nanopore and inside the probe structure, single or multiple times; and displacement means configured to ...
2023Bubble-enhanced ultrasonic microfluidic chip for rapid DNA fragmentation
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DNA fragmentation is an essential process in developing genetic sequencing strategies, genetic research, as well as for the diagnosis of diseases with a genetic signature like cancer. Efficient on-chip DNA fragmentation protocols would be beneficial to pro ...
ROYAL SOC CHEMISTRY2022