Aging brainAging of the brain is a process of transformation of the brain in older age, including changes all individuals experience and those of illness (including unrecognised illness). Usually this refers to humans. Since life extension is only pertinent if accompanied by health span extension, and, more importantly, by preserving brain health and cognition, finding rejuvenating approaches that act simultaneously in peripheral tissues and in brain function is a key strategy for development of rejuvenating technology.
Sea level riseBetween 1901 and 2018, the average global sea level rose by , or an average of 1–2 mm per year. This rate accelerated to 4.62 mm/yr for the decade 2013–2022. Climate change due to human activities is the main cause. Between 1993 and 2018, thermal expansion of water accounted for 42% of sea level rise. Melting temperate glaciers accounted for 21%, with Greenland accounting for 15% and Antarctica 8%. Sea level rise lags changes in the Earth's temperature.
ModafinilModafinil, sold under the brand name Provigil among others, is a central nervous system (CNS) stimulant medication used to treat sleepiness due to narcolepsy, shift work sleep disorder, and obstructive sleep apnea. While it has seen off-label use as a purported cognitive enhancer to improve wakefulness in animal and human studies, the research on its effectiveness for this use is not conclusive. Modafinil is taken by mouth. Modafinil's side effects include headaches, anxiety, excessive adrenal gland overproduction, and nausea.