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Immune cells are exquisitely sensitive to the mechanical properties of cancer cells. Soft cancer cells can avoid immune-mediated destruction. Therapeutically targeting this mechanical immune checkpoint may enhance the efficacy of cancer immunotherapy.
Didier Trono, Priscilla Turelli, Evaristo Jose Planet Letschert, Filipe Amândio Brandão Sanches Vong Martins, Florian Huber, Olga Marie Louise Rosspopoff, Romain Forey, Sandra Eloise Kjeldsen, Cyril David Son-Tuyên Pulver, Joana Carlevaro Fita