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Quantitative Microstructural Imaging for Clinical Use

Gian Franco Piredda

Today, Magnetic Resonance Imaging (MRI) is a well-established medical imaging modality thanks to its excellent soft tissue contrast. Conventional MR image contrasts can be weighted towards one or more physical properties that discriminate different tissues ...

EPFL2021

Purpose To develop a 3D MR technique to simultaneously acquire proton multiparametric maps (T-1, T-2, and proton density) and sodium density weighted images over the whole brain. Methods We implemented a 3D stack-of-stars MR pulse sequence which consists o ...

WILEY2021

Habitat Néo Rural, Biorégion de la Calanca: construction d’un scénario d’habitat humain alternatif à partir d’un territoire rural à l’abandon

Pietro Berta, Simone Izzo

Il est peut-être redondant d’affirmer que l'urgence climatique et la transition écologique doivent être traitées comme des priorités par le monde politique. Il l'est certainement moins de rappeler que la contribution de l'architecte peut constituer un réel ...

2021

Magnetic resonance resonance (MRI) is a widely used modality to obtain in vivo tissue information. Clinical applications are near countless, and almost all body parts can be examined using an MR scanner. As the method is non invasive, does not use ionizing ...

EPFL2020

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The presence of cortical lesions in multiple sclerosis patients has emerged as an important biomarker of the disease. They appear in the earliest stages of the illness and have been shown to correlate with the severity of clinical symptoms. However, cortic ...

2020

RimNet: A deep 3D multimodal MRI architecture for paramagnetic rim lesion assessment in multiple sclerosis

Meritxell Bach Cuadra, Tobias Kober, Cristina Granziera, Francesco La Rosa, Hamza Kebiri, Po-Jui Lu

Objectives In multiple sclerosis (MS), the presence of a paramagnetic rim at the edge of non-gadolinium-enhancing lesions indicates perilesional chronic inflammation. Patients featuring a higher paramagnetic rim lesion burden tend to have more aggressive d ...

2020

3-Dimensional magnetic resonance imaging of the freely moving human eye

Jérôme Yerly, Lorenzo Di Sopra, Josefina Adriana Maria Bastiaansen, João Pedro Forjaco Jorge, Silvio Ionta, Benedetta Franceschiello, David Zeugin

Eye motion is a major confound for magnetic resonance imaging (MRI) in neuroscience or ophthalmology. Currently, solutions toward eye stabilisation include participants fixating or administration of paralytics/anaesthetics. We developed a novel MRI protoco ...

PERGAMON-ELSEVIER SCIENCE LTD2020

Data-driven Measurement Designs for Magnetic Resonance Imaging

Baran Gözcü

Despite being a powerful medical imaging technique which does not emit any ionizing radiation, magnetic resonance imaging (MRI) always had the major problem of long scanning times that can take up to an hour depending on the application. It also requires u ...

EPFL2019

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Background and purpose. - Automated synthetic magnetic resonance imaging (MRI) provides qualitative, weighted image contrasts as well as quantitative information from one scan and is well-suited for various applications such as analysis of white matter dis ...

MASSON EDITEUR2019

Fast model-based T-2 mapping using SAR-reduced simultaneous multislice excitation

Jean-Philippe Thiran, Tobias Kober, Tom Hilbert, José Pedro Rebelo Ferreira Marques

Purpose To obtain whole-brain high-resolution T-2 maps in 2 minutes by combining simultaneous multislice excitation and low-power PINS (power independent of number of slices) refocusing pulses with undersampling and a model-based reconstruction. Methods A ...

WILEY2019