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Fading of brain network fingerprint in Parkinson's disease predicts motor clinical impairment
Related publications (37)
Differential Impact of Brain Network Efficiency on Poststroke Motor and Attentional Deficits
Dimitri Nestor Alice Van De Ville, Friedhelm Christoph Hummel, Gabriel Girard, Takuya Morishita, Elena Beanato, Lisa Aïcha Mireille Julie Fleury, Maximilian Jonas Wessel, Philipp Johannes Koch, Philip Egger, Andéol Geoffroy Cadic-Melchior
Background:Most studies on stroke have been designed to examine one deficit in isolation; yet, survivors often have multiple deficits in different domains. While the mechanisms underlying multiple-domain deficits remain poorly understood, network-theoretic ...
2023An attention-based deep learning approach for the classification of subjective cognitive decline and mild cognitive impairment using resting-state EEG
Silvestro Micera, Michael Lassi
Objective. This study aims to design and implement the first deep learning (DL) model to classify subjects in the prodromic states of Alzheimer's disease (AD) based on resting-state electroencephalographic (EEG) signals. Approach. EEG recordings of 17 heal ...
IOP Publishing Ltd2023Brain connectome correlates of short-term motor learning in healthy older subjects
Friedhelm Christoph Hummel, Takuya Morishita, Manon Chloé Durand-Ruel, Chang-Hyun Park, Maeva Moyne
The motor learning process entails plastic changes in the brain, especially in brain network reconfigurations. In the current study, we sought to characterize motor learning by determining changes in the coupling behaviour between the brain functional and ...
Paris2023Simulating the progression of brain structural alterations in Parkinson's disease
Considering brain structural alterations as neurodegenerative consequences of Parkinson's disease (PD), we sought to infer the progression of PD via the ordering of brain structural alterations from cross-sectional MRI observations. Having measured cortica ...
NATURE PORTFOLIO2022Alpha-synuclein as a Potential Biomarker for Parkinson’s Disease and Other Synucleinopathies: Gaps, Challenges, and Opportunities
Parkinson's disease (PD), the second most common progressive neurodegenerative disease, develops and progresses for 10-15 years before the clinical diagnostic symptoms of the disease are manifested. Furthermore, several aspects of PD pathology overlap with ...
2022Opportunities and challenges of alpha-synuclein as a potential biomarker for Parkinson's disease and other synucleinopathies
Hilal Lashuel, Pedro José Santana Ribeiro Magalhães
Parkinson's disease (PD), the second most common progressive neurodegenerative disease, develops and progresses for 10-15 years before the clinical diagnostic symptoms of the disease are manifested. Furthermore, several aspects of PD pathology overlap with ...
NATURE PORTFOLIO2022Improving Functional Connectome Fingerprinting with Degree-Normalization
Background: Functional connectivity quantifies the statistical dependencies between the activity of brain regions, measured using neuroimaging data such as functional magnetic resonance imaging (fMRI) blood-oxygenation-level dependent time series. The netw ...
MARY ANN LIEBERT, INC2022Investigating cognitive ability using action-based models of structural brain networks
Recent developments in network neuroscience have highlighted the importance of developing techniques for analysing and modelling brain networks. A particularly powerful approach for studying complex neural systems is to formulate generative models that use ...
OXFORD UNIV PRESS2022Clinical connectome fingerprints of cognitive decline
Enrico Amico, Emahnuel Troisi Lopez
Brain connectome fingerprinting is rapidly rising as a novel influential field in brain network analysis. Yet, it is still unclear whether connectivity fingerprints could be effectively used for mapping and predicting disease progression from human brain d ...
2021Plasma neurofilament light and phosphorylated tau 181 as biomarkers of Alzheimer's disease pathology and clinical disease progression
Bénédicte Marie Maréchal, Jonas Richiardi, Christopher Clark
BackgroundTo assess the performance of plasma neurofilament light (NfL) and phosphorylated tau 181 (p-tau181) to inform about cerebral Alzheimer's disease (AD) pathology and predict clinical progression in a memory clinic setting.MethodsPlasma NfL and p-ta ...
BMC2021