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Identification of biopsychological trait markers in functional neurological disorders
Related publications (68)
Transient resting-state salience-limbic co-activation patterns in functional neurological disorders
Thomas William Arthur Bolton, Serafeim Loukas
Background: Functional neurological disorders were historically regarded as the manifestation of a dynamic brain lesion which might be linked to trauma or stress, although this association has not yet been directly tested yet. Analysing large-scale brain n ...
Elsevier Sci Ltd2024Amygdala volumes and associations with socio-emotional competencies in preterm youth: cross-sectional and longitudinal data
Elda Fischi Gomez, Laura Ioana Gui, Vanessa Siffredi, Petra Susan Hüppi
Background Socio-emotional difficulties often result from very preterm (VPT) birth. The amygdala's developmental trajectory, including its nuclei, has been recognized as a significant factor in observed difficulties. This study aims to assess the relations ...
Springernature2024Glucocorticoid-based pharmacotherapies preventing PTSD
Maria del Carmen Sandi Perez, Silvia Monari
Posttraumatic stress disorder (PTSD) is a highly disabling psychiatric condition that may arise after exposure to acute and severe trauma. It is a highly prevalent mental disorder worldwide, and the current treatment options for these patients remain limit ...
PERGAMON-ELSEVIER SCIENCE LTD2023Blunted Glucocorticoid Responsiveness to Stress Causes Behavioral and Biological Alterations That Lead to Posttraumatic Stress Disorder Vulnerability
Maria del Carmen Sandi Perez, Jocelin Grosse, Olivia Zanoletti, Simone Astori, Sophie Elizabeth Walker, Silvia Monari
Background: Understanding why only a subset of trauma-exposed individuals develop posttraumatic stress disorder is critical for advancing clinical strategies. A few behavioral (deficits in fear extinction) and biological (blunted glucocorticoid levels, sma ...
2023Genetic selection for low glucocorticoid responsiveness recapitulates PTSD-related phenotypes: a behavioral, neuroimaging and sleep-physiology study
Humans show inter-individual differences in vulnerability to develop post-traumatic stress disorder (PTSD) following exposure to trauma. Several critical biobehavioral features have been consistently described in PTSD patients, including blunted cortisol l ...
EPFL2022Exploring associations between diurnal cortisol, stress, coping and psychopathology in adolescents and young adults with 22q11.2 deletion syndrome
Maria del Carmen Sandi Perez, Olivia Zanoletti, Maude Schneider, Farnaz Delavari
Background: 22q11.2 deletion syndrome (22q11DS) is a neurogenetic condition associated to a high risk for psychiatric disorders, including psychosis. Individuals with 22q11DS are thought to experience increased levels of chronic stress, which could lead to ...
2022Multi-centre classification of functional neurological disorders based on resting-state functional connectivity
Dimitri Nestor Alice Van De Ville, Jonas Richiardi
Background: Patients suffering from functional neurological disorder (FND) experience disabling neurological symptoms not caused by an underlying classical neurological disease (such as stroke or multiple sclerosis). The diagnosis is made based on reliable ...
ELSEVIER SCI LTD2022Identifying Disease-Specific Neural Reactivity to Psychosocial Stress in Borderline Personality Disorder
Dimitri Nestor Alice Van De Ville
BACKGROUND: Patients with borderline personality disorder (BPD) typically present emotion dysregulation (ED) when faced with adversity. However, it is argued that altered stress response may be more influenced by ED than BPD-specific traits. Here, we inves ...
ELSEVIER2022Neural Annotation Refinement: Development of a New 3D Dataset for Adrenal Gland Analysis
Pascal Fua, Jiancheng Yang, Pamuditha Udaranga Wickramasinghe, Rui Shi
The human annotations are imperfect, especially when produced by junior practitioners. Multi-expert consensus is usually regarded as golden standard, while this annotation protocol is too expensive to implement in many real-world projects. In this study, w ...
SPRINGER INTERNATIONAL PUBLISHING AG2022Antibody-Coated Wearable Organic Electrochemical Transistors for Cortisol Detection in Human Sweat
Danick Briand, Marwan El Chazli, Silvia Demuru, Jaemin Kim
The dysregulation of the hormone cortisol is related to several pathological states, and its monitoring could help prevent severe stress, fatigue, and mental diseases. While wearable antibody-based biosensors could allow real-time and simple monitoring of ...
AMER CHEMICAL SOC2022