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Streamline RimNet: Tools for Automatic Classification of Paramagnetic Rim Lesions in MRI of Multiple Sclerosis

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Recent applications of UHF-MRI in the study of human brain function and structure: a review

Wietske Van der Zwaag, José Pedro Rebelo Ferreira Marques

The increased availability of ultra-high-field (UHF) MRI has led to its application in a wide range of neuroimaging studies, which are showing promise in transforming fundamental approaches to human neuroscience. This review presents recent work on structu ...

Wiley-Blackwell2016

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Background: Cerebellar pathology occurs in late multiple sclerosis (MS) but little is known about cerebellar changes during early disease stages. In this study, we propose a new multicontrast “connectometry” approach to assess the structural and functional ...

Wiley-Blackwell2015

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Introduction. Local microstructural pathology in multiple sclerosis patients might influence their clinical performance. This study applied multicontrast MRI to quantify inflammation and neurodegeneration in MS lesions. We explored the impact of MRI-based ...

Hindawi Publishing Corporation2015

Advanced MRI unravels the nature of tissue alterations in early multiple sclerosis

Jean-Philippe Thiran, David Paul Roger Romascano, Cristina Granziera, Djalel Eddine Meskaldji, Alexis Roche, Guillaume Bonnier, Ying-Chia Lin, Gloria Menegaz

In patients with multiple sclerosis (MS), conventional magnetic resonance imaging (MRI) provides only limited insights into the nature of brain damage with modest clinic-radiological correlation. In this study, we applied recent advances in MRI techniques ...

2014

Hyperpolarized Magnetic Resonance as a Sensitive Detector of Metabolic Function

Arnaud Comment

Hyperpolarized magnetic resonance allows for noninvasive measurements of biochemical reactions in vivo. Although this technique provides a unique tool for assaying enzymatic activities in intact organs, the scope of its application is still elusive for the ...

Amer Chemical Soc2014

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Imaging the connectome in vivo has become feasible through the integration of several rapidly developing fields of science and engineering, namely magnetic resonance imaging and in particular diffusion MRI on one side, image processing and network theory o ...

Elsevier2013

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Objectives: Lesion detection and characterization in multiple sclerosis (MS) are an essential part of its clinical diagnosis and an important research field. In this pilot study, we applied the recently introduced two inversion-contrast magnetization-prepa ...

2012

Structural Magnetic Resonance Imaging

Tobias Kober

Notwithstanding its great success in diagnostic routine and research, structural magnetic resonance imaging (MRI) still faces challenges. In this context, the present thesis studies new approaches to mitigate the motion susceptibility of MRI. Furthermore, ...

EPFL2011

A pipeline approach with spatial information for segmenting multiple sclerosis lesions on brain magnetic resonance imaging

Meritxell Bach Cuadra, Mariano Cabezas Grebol

Conventional magnetic resonance imaging (MRI) techniques are highly sensitive to detect multiple sclerosis (MS) plaques, enabling a quantitative assessment of inﬂammatory activity and lesion load. In quantitative analysis of focal lesions, manual or semi-a ...

2011

Toward Reliable MR-Based Brain Structure Morphometry

Bénédicte Marie Maréchal

Dementing neurodegenerative disorders have more and more prominent public health implications with the most frequent cause being the currently non reversible Alzheimer's Disease (AD). However, over the past 15 years, an abundant literature has demonstrated ...

EPFL2011