Publication

Streamline RimNet: Tools for Automatic Classification of Paramagnetic Rim Lesions in MRI of Multiple Sclerosis

Related publications (35)

CVSnet: A machine learning approach for automated central vein sign assessment in multiple sclerosis

Meritxell Bach Cuadra, Tobias Kober, Reto Meuli, Cristina Granziera, Jonas Richiardi, João Pedro Forjaco Jorge, Mario Joao Fartaria de Oliveira, Francesco La Rosa

The central vein sign (CVS) is an efficient imaging biomarker for multiple sclerosis (MS) diagnosis, but its application in clinical routine is limited by inter-rater variability and the expenditure of time associated with manual assessment. We describe a ...
2020

Multiple sclerosis cortical and WM lesion segmentation at 3T MRI: a deep learning method based on FLAIR and MP2RAGE

Jean-Philippe Thiran, Meritxell Bach Cuadra, Cristina Granziera, Muhamed Barakovic, Mario Joao Fartaria de Oliveira, Francesco La Rosa, Ahmed Abdulkadir, Po-Jui Lu

The presence of cortical lesions in multiple sclerosis patients has emerged as an important biomarker of the disease. They appear in the earliest stages of the illness and have been shown to correlate with the severity of clinical symptoms. However, cortic ...
2020

Automated Detection and Segmentation of Multiple Sclerosis Lesions Using Ultra-High-Field MP2RAGE

Meritxell Bach Cuadra, Tobias Kober, Cristina Granziera, Mario Joao Fartaria de Oliveira, Kieran O'Brien

Objectives The aim of this study was to develop a new automated segmentation method of white matter (WM) and cortical multiple sclerosis (MS) lesions visible on magnetization-prepared 2 inversion-contrast rapid gradient echo (MP2RAGE) images acquired at 7 ...
LIPPINCOTT WILLIAMS & WILKINS2019

Longitudinal analysis of white matter and cortical lesions in multiple sclerosis

Meritxell Bach Cuadra, Tobias Kober, Cristina Granziera, Mario Joao Fartaria de Oliveira

Purpose: The goals of this study were to assess the performance of a novel lesion segmentation tool for longitudinal analyses, as well as to validate the generated lesion progression map between two time points using conventional and non-conventional MR se ...
2019

Clinical Neuroimaging Using 7 T MRI: Challenges and Prospects

Rolf Gruetter, Lijing Xin, Özlem Ipek, Pascal Martelli, François Lazeyras

The aim of this article is to illustrate the principal challenges, from the medical and technical point of view, associated with the use of ultrahigh field (UHF) scanners in the clinical setting and to present available solutions to circumvent these limita ...
2018

Enhanced Student Learning in Proteomics - an Interactive Tool Support for Teaching Workflows

Teaching and learning support for bioinformatics has become a popular research area. Proteomics education can be bridged with technology enhancements such that tool support for protein structures experiments. Generally, students in proteomics require diffe ...
IEEE2018

An Ultra-High Field Study of Cerebellar Pathology in Early Relapsing-Remitting Multiple Sclerosis Using MP2RAGE

Meritxell Bach Cuadra, Tobias Kober, Cristina Granziera, Alexis Roche, Guillaume Bonnier, Mario Joao Fartaria de Oliveira, Kieran O'Brien, Pavel Falkovskiy

Objectives: The aim of this study was to study focal cerebellar pathology in early stages of multiple sclerosis (MS) using ultra-high-field magnetization-prepared 2 inversion-contrast rapid gradient-echo (7T MP2RAGE). Materials and Methods: Twenty early-st ...
Lippincott, Williams & Wilkins2017

Dynamo Catalogue: Geometrical tools and data management for particle picking in subtomogram averaging of cryo-electron tomograms

Henning Paul-Julius Stahlberg

Cryo electron tomography allows macromolecular complexes within vitrified, intact, thin cells or sections thereof to be visualized, and structural analysis to be performed in situ by averaging over multiple copies of the same molecules. Image processing fo ...
Elsevier BV2017

A Longitudinal Study of Neurite Orientation Dispersion and Density Imaging in Relapsing-Remitting Multiple Sclerosis

Jean-Philippe Thiran, David Paul Roger Romascano, Elda Fischi Gomez, Alessandro Daducci, Cristina Granziera, Gunnar Krüger, Guillaume Bonnier

We explored the sensitivity of a novel diffusion MRI method i.e. “Neurite orientation dispersion and density imaging”, to detect and characterize brain microstructure alterations in relapsing-remitting multiple sclerosis patients that we followed up over 2 ...
2017

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