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Spatially multiplexed single-molecule translocations through a nanopore at controlled speeds

Related publications (33)

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Electronic readout of DNA amplification in nanoliter chambers. Strategies towards highly parallel semiconductor-based nucleic acid amplification testing.

Saurabh Tomar

Polymerase chain reaction (PCR) has been the most significant driver in the field of nucleic acid testing (NAT) since its invention. Popularized as an abbreviation by the Covid-19 pandemic, PCR-based methods are the gold standard in the field of diagnostic ...

EPFL2023

The evolution of the 3D morphology is at the center of many relevant biological processes ranging from cellular differentiation to cancer invasion and metastasis. Microscopy techniques, such as electron microscopy (EM), super-resolution (SR) optical micros ...

EPFL2023

Transfer learning application of self-supervised learning in ARPES

Gabriel Aeppli

There is a growing recognition that electronic band structure is a local property of materials and devices, and there is steep growth in capabilities to collect the relevant data. New photon sources, from small-laboratory-based lasers to free electron lase ...

IOP Publishing Ltd2023

Genetic-Optimized Pulse Coding Technique for Brillouin Distributed Optical Fiber Sensing

Luc Thévenaz, Marcelo Alfonso Soto Hernandez, Zhisheng Yang, Simon Adrien Zaslawski, Sheng Wang, Jian Wu

A single code sequence designed by a genetic searching algorithm is proposed to enhance the signal-to-noise ratio of Brillouin distributed sensors without hardware modification, enabling high-performance and cost-effective sensing over a 200-km-loop setup. ...

2020

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A light microscope comprises a light source (10) for illuminating a specimen (35), a photon-counting detector array (60) with a plurality of photon-counting detector elements (61-64) for measuring detection light (15) coming from the specimen (35), wherein ...

2020

Impact of Fitting and Digital Filtering on Signal-to-Noise Ratio and Brillouin Frequency Shift Uncertainty of BOTDA Measurements

Luc Thévenaz, Marcelo Alfonso Soto Hernandez, Zhisheng Yang, Simon Adrien Zaslawski

The intricate relationships linking signal-to-noise ratio and Brillouin frequency shift uncertainty after post-processing of Brillouin optical time-domain analysis measurements are investigated, highlighting the crucial impact of fitting. ...

OSA2018

Interactions of proteins with DNA are essential for carrying out DNA's biological functions and performing a cellular cycle. Such processes as DNA replication, expression and repair are performed by an organised action of various proteins. To better unders ...

EPFL2017

Intensifying the response of distributed optical fibre sensors using 2D and 3D image restoration

Luc Thévenaz, Marcelo Alfonso Soto Hernandez

Distributed optical fibre sensors possess the unique capability of measuring the spatial and temporal map of environmental quantities that can be of great interest for several field applications. Although existing methods for performance enhancement have e ...

Nature Publishing Group2016

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We report on noise-induced spin ordering in a collective quasiparticle system: spinor stochastic resonance. Synergetic interplay of a polarization-modulated signal and a polarization noise allows us to switch coherently between the two metastable states of ...

American Physical Society2015

Local electronic properties and adsorption conformations of molecular nanostructures at surfaces

Ivan Pentegov

Nanoscale science is an emerging field of our time and opens a broad horizon for applications in almost every area of human activity, from medicine to energy storage. As usual, there are numerous challenges in the way of progress, which slow down the devel ...

EPFL2015