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Observed Kinetics of Enterovirus Inactivation by Disinfectants Differ among the Host Cells Used for Enumeration
Related publications (32)
Observed Kinetics of Enterovirus Inactivation by Free Chlorine Are Host Cell-Dependent
Tamar Kohn, Shannon Christa David, Shotaro Torii, Federica Cariti
Virucidal efficacies of disinfectants are typically assessed by infectivity assay utilizing a single type of host cell. Enteroviruses infect multiple host cells via various entry routes, and each entry route may be impaired differently by a given disinfect ...
2023Inactivation of coxsackievirus B5 by free chlorine under conditions relevant to drinking water treatment
Chlorine disinfection is commonly applied to inactivate pathogenic viruses in drinking water treatment plants. However, the role of water quality in chlorine disinfection of viruses has not been investigated thoughtfully. In this study, we investigated the ...
IWA PUBLISHING2023Oxidative Water Treatment: The Track Ahead
Chemical oxidation has been applied in municipal water treatment for more than a century, initially for disinfection. In the early decades, chlorine disinfection was adopted in the fight against waterborne disease. However, the oxidative properties of chlo ...
2023Kinetic and mechanistic understanding of chlorite oxidation during chlorination: Optimization of ClO2 pre-oxidation for disinfection byproduct control
Chlorine dioxide (ClO2) applications to drinking water are limited by the formation of chlorite (ClO2-) which is regulated in many countries. However, when ClO2 is used as a pre-oxidant, ClO2- can be oxidized by chlorine during subsequent disinfection. In ...
PERGAMON-ELSEVIER SCIENCE LTD2022Reactions of alpha,beta-Unsaturated Carbonyls with Free Chlorine, Free Bromine, and Combined Chlorine
Chemical disinfectants employed in water and wastewater treatment can produce a variety of transformation products, including carbonyl compounds (e.g., saturated and unsaturated aldehydes and ketones). Experiments conducted under conditions relevant to chl ...
AMER CHEMICAL SOC2021Adaptation of Human Enterovirus to Warm Environments Leads to Resistance against Chlorine Disinfection
Tamar Kohn, Anna Carratala Ripolles, Virginie Bachmann, Timothy R. Julian
Sunlight, temperature, and microbial grazing are among the environmental factors promoting the inactivation of viral pathogens in surface waters. Globally, these factors vary across time and space. The persistence of viral pathogens, and ultimately their e ...
2020Chlorination of Phenols Revisited: Unexpected Formation of α,β-Unsaturated C4-Dicarbonyl Ring Cleavage Products
Despite decades of research on the fate of phenolic compounds when water is disinfected with hypochlorous acid (HOCl), there is still considerable uncertainty regarding the formation mechanisms and identity of ring cleavage products, especially at higher c ...
2020Susceptibility of Enterovirus B strains to disinfectants and heat
The susceptibility of waterborne viruses to different inactivating treatments is acknowledged to vary between viruses and even between closely related strains, yet the extent of this variation, or the underlying mechanisms, are not known. Here, different e ...
EPFL2019Micropollutant Oxidation Studied by Quantum Chemical Computations: Methodology and Applications to Thermodynamics, Kinetics, and Reaction Mechanisms
Urs von Gunten, Minju Lee, Peter Rudolf Tentscher
The abatement of organic micropollutants during oxidation processes has become an emerging issue for various urban water systems such as drinking water, wastewater, and water reuse. Reaction kinetics and mechanisms play an important role in terms of effici ...
AMER CHEMICAL SOC2019Variability in Disinfection Resistance between Currently Circulating Enterovirus B Serotypes and Strains
Tamar Kohn, Simon Meister, Marius Klinger, Matthew Eric Verbyla
The susceptibility of waterborne viruses to disinfection is known to vary between viruses and even between closely related strains, yet the extent of this variation is not known. Here, different enteroviruses (six strains of coxsackievirus B5, two strains ...
2018