Publications related to Innovative Biomarkers for Obesity and Type 1 Diabetes Based on Bifidobacterium and Metabolomic Profiling

Implantable enzyme amperometric biosensors

The implantable enzyme amperometric biosensor continues as the dominant in vivo format for the detection, monitoring and reporting of biochemical analytes related to a wide range of pathologies. Widely used in animal studies, there is increasing emphasis o ...

2012

Beta amyloid and hyperphosphorylated tau deposits in the pancreas in type 2 diabetes

László Forró, Aleksandra Radenovic, Andras Kis

Strong epidemiologic evidence suggests an association between Alzheimer disease (AD) and type 2 diabetes. To determine if amyloid beta (A

\beta

) and hyperphosphorylated tau occurs in type 2 diabetes, pancreas tissues from 21 autopsy cases (10 type 2 diabe ...

Elsevier2010

Targeting the TGR5-GLP-1 pathway to combat type 2 diabetes and non-alcoholic fatty liver disease

Johan Auwerx, Kristina Schoonjans, Thijs Pols

Incretin-based therapies have shown promise in the treatment of type 2 diabetes. Here we review our current understanding of TGR5 as a target to induce glucagon-like peptide-1 (GLP-1) secretion. These new observations suggest that TGR5 agonists may constit ...

Elsevier Masson2010

The gait and balance of patients with diabetes can be improved: a randomised controlled trial

Kamiar Aminian, Stéphane Armand

Gait characteristics and balance are altered in diabetic patients. Little is known about possible treatment strategies. This study evaluates the effect of a specific training programme on gait and balance of diabetic patients. ...

2010

Insights on EVA lamination process: Where do the bubbles come from?

Christophe Ballif, Hengyu Li, Laure-Emmanuelle Perret Aebi

• The identification and control of volatile organic compounds (VOCs) released by polymers during lamination in the photovoltaic (PV) industry is of considerable importance to establish and optimize processes in order to ensure a long term reliability of t ...

2010

In vivo imaging of murine endocrine islets of Langerhans with extended-focus optical coherence microscopy

Theo Lasser, Michael Friedrich, Rainer Leitgeb, Anne Grapin-Botton, Martin Villiger, Joan Goulley

Aims/hypothesis Structural and functional imaging of the islets of Langerhans and the insulin-secreting beta cells represents a significant challenge and a long-lasting objective in diabetes research. In vivo microscopy offers a valuable insight into beta ...

Springer Verlag2009

PGC-1alpha, SIRT1 and AMPK, an energy sensing network that controls energy expenditure

Johan Auwerx, Carlos Canto Alvarez

PURPOSE OF REVIEW: Peroxisome proliferator-activated receptor gamma coactivator-1-alpha (PGC-1alpha) has been extensively described as a master regulator of mitochondrial biogenesis. However, PGC-1alpha activity is not constant and can be finely tuned in r ...

2009

Caffeine consumption attenuates neurochemical modifications in the hippocampus of streptozotocin-induced diabetic rats

Rolf Gruetter, João Miguel das Neves Duarte

Type 1 diabetes can affect hippocampal function triggering cognitive impairment through unknown mechanisms. Caffeine consumption prevents hippocampal degeneration and memory dysfunction upon different insults and is also known to affect peripheral glucose ...

Wiley-Blackwell2009

The prolyl-aminodipeptidases and their inhibitors as therapeutic targets for fibrogenic disorders

Sandrine Gerber

Many biologically active peptides are protected from general proteolytic degradation by evolutionary conserved prolines (Pro), due to conformational constraints imposed by the Pro residue. Thus the biological importance of prolyl-specific peptidases points ...

2009

Preventive and/or therapeutic agents for diabetes

Johan Auwerx

A preventive and/or therapeutic agent for diabetes, comprising a substance capable of inhibiting the activity of farnesoid X receptor as an active ingredient ...

2006

Innovative Biomarkers for Obesity and Type 1 Diabetes Based on Bifidobacterium and Metabolomic Profiling

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Implantable enzyme amperometric biosensors

Beta amyloid and hyperphosphorylated tau deposits in the pancreas in type 2 diabetes

Targeting the TGR5-GLP-1 pathway to combat type 2 diabetes and non-alcoholic fatty liver disease

The gait and balance of patients with diabetes can be improved: a randomised controlled trial

Insights on EVA lamination process: Where do the bubbles come from?

In vivo imaging of murine endocrine islets of Langerhans with extended-focus optical coherence microscopy

PGC-1alpha, SIRT1 and AMPK, an energy sensing network that controls energy expenditure

Caffeine consumption attenuates neurochemical modifications in the hippocampus of streptozotocin-induced diabetic rats

The prolyl-aminodipeptidases and their inhibitors as therapeutic targets for fibrogenic disorders

Preventive and/or therapeutic agents for diabetes

Insights on EVA lamination process: Where do the bubbles come from?

The prolyl-aminodipeptidases and their inhibitors as therapeutic targets for fibrogenic disorders

Targeting the TGR5-GLP-1 pathway to combat type 2 diabetes and non-alcoholic fatty liver disease

Beta amyloid and hyperphosphorylated tau deposits in the pancreas in type 2 diabetes

The gait and balance of patients with diabetes can be improved: a randomised controlled trial

In vivo imaging of murine endocrine islets of Langerhans with extended-focus optical coherence microscopy

PGC-1alpha, SIRT1 and AMPK, an energy sensing network that controls energy expenditure

Caffeine consumption attenuates neurochemical modifications in the hippocampus of streptozotocin-induced diabetic rats

Preventive and/or therapeutic agents for diabetes

Implantable enzyme amperometric biosensors