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Amorphous membrane blending

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Self-replication of complex digital circuits in programmable logic devices

Joël Rossier

Nature is an incredibly complex system resulting from the interactions of many different interdependent species, composed of many individual organisms, which are in turn composed of an extremely large number of cells. In multi-cellular organisms, the paral ...

EPFL2008

Single-molecule motions of oligoarginine transporter conjugates on the plasma membrane of Chinese hamster ovary cells

Hui Wang

To explore the real-time dynamic behavior of molecular transporters of the cell-penetrating-peptide (CPP) type on a biological membrane, single fluorescently labeled oligoarginine conjugates were imaged interacting with the plasma membrane of Chinese hamst ...

2008

Membrane protein research depends largely on the availability of functional protein in an instrumental set- up for application of biophysical investigations. We used an in vitro synthesis strategy in the presence of a solid supported lipid membrane as a ne ...

2007

In vitro Synthesis of GPCRs in a Solid Supported Planar Lipid Membrane System

Theo Lasser, Marcel Leutenegger

Membrane protein research depends largely on the availability of functional protein in an instrumental set-up for application of biophysical investigations. We used an in vitro synthesis strategy in the presence of a solid supported lipid membrane as a new ...

2007

Pervasive Computing with Frugal Objects

Rachid Guerraoui, Maxime Monod, Benoît Garbinato, Jesper Honig Spring

This paper presents a computing model for resource-limited mobile devices that might be ubiquitously deployed in private and business environments. The model integrates a strongly-typed event-based communication paradigm with abstractions for frugal contro ...

2007

Multifunctional Lipid/Quantum-Dots Hybrid Nanocontainers for Controlled Targeting of Live Cells

Horst Vogel, Davide Demurtas, Pierre-Yves Bolinger, Christophe Danelon, Jacques Dubochet, Paulina Izewska, Gopakumar Gopalakrishnan

In this communication, we report on an interesting observation of wide-ranging potential for cellular imaging and manipulation: Hydrophobic QDs can be easily incorporated into the bilayer membrane of lipid vesicles. Such lipid/QD nanocontainer hybrid vesic ...

2006

The bacterial toxin aerolysin kills cells by forming heptameric channels, of unknown structure, in the plasma membrane. Using disulfide trapping and cysteine scanning mutagenesis coupled to thiol-specific labeling on lipid bilayers, we identify a loop that ...

2006

Lipid membranes for the fabrication of functional micro- and nano-structures

Gopakumar Gopalakrishnan

The central goal of this thesis work is to fabricate novel, functional fluorescent nanostructures in confined systems offered by phospholipid membranes, which are known to have highly ordered, thermotropic and lyotropic structures. In separate approaches, ...

EPFL2006

Frugal Mobile Objects

Rachid Guerraoui, Maxime Monod, Benoît Garbinato, Jesper Honig Spring

This paper presents a computing model for resource-limited mobile devices. The originality of the model lies in the integration of a stronglytyped event-based communication paradigm with abstractions for frugal control, assuming a small footprint runtime. ...

2006

Tension-induced fusion of bilayer membranes and vesicles

Julian Charles Shillcock

Maintaining the integrity of their protective plasma membrane is a primary requirement of cells. Accordingly, cellular events that breach the membrane are tightly regulated1. Artificial vesicles used in drug delivery must also stay intact until they have r ...

Nature Publishing Group2005