Total chemical synthesis, characterization and immunological properties of a MHC class I model using the TASP concept for protein de novo design
Related publications (47)
Graph Chatbot
Chat with Graph Search
Ask any question about EPFL courses, lectures, exercises, research, news, etc. or try the example questions below.
DISCLAIMER: The Graph Chatbot is not programmed to provide explicit or categorical answers to your questions. Rather, it transforms your questions into API requests that are distributed across the various IT services officially administered by EPFL. Its purpose is solely to collect and recommend relevant references to content that you can explore to help you answer your questions.
The aim of this project was to investigate and quantify the impact of certain early design decisions on the solar potential of a target building placed in an urban context. This was done through a parametric study based on the successive variation of speci ...
An approach to the synthesis of polyhydroxyazepane derivatives from sugar-based epoxyamides or epoxyalcohols, in which the total regioselective epoxide opening by nitrogen nucleophiles is the key step, is described. Thus, novel polyhydroxyazepane carboxami ...
This paper outlines the theoretical background of the punching shear provisions implemented in the fib Model Code 2010 and presents a practical example of its applica tion. It is the aim to explain the mechanical model that forms the basis of the punching ...
A recommender system is a Web technology that proactively suggests items of interest to users based on their objective behavior or explicitly stated preferences. Evaluations of recommender systems (RS) have traditionally focused on the performance of algor ...
Bicyclic peptides are small, constrained peptides that can bind with high affinity and selectivity to protein targets. Their small size provides a number of advantages over larger protein-based ligands, including access to chemical synthesis, better tissue ...
This book addresses the impact of nanotechnologies on the design of electronic systems. Coverage includes technologies ranging from nanoelectronics to sensing and micro/nanofluidics, and encompassing techniques that bridge the gap between engineering and b ...
Systems-on-Chips (SoCs) integrate more and more heterogeneous components: analog/RF/digital circuits, sensors, actuators, software. For the design of these systems very different description formalisms, or Models of Computation (MoCs), and tools are used f ...
Ligands based on bicyclic peptides can combine favourable properties of antibodies (good binding affinity and target specificity) and small molecule ligands (stability, access to chemical synthesis, diffusion properties) and might be suitable molecular str ...
In late 2007 the ALICE design studio at EPFL was invited by the Swiss government to participate as part of the Swiss exhibition in the Swiss Pavilion in the Giardini in the Venice Architecture Biennale 2008. The exhibition was to expose research and teachi ...
As the world becomes more interdependent and computing grows more collaborative, there is a need for new abstractions and tools to help users work together. We recently introduced entangled queries – a mechanism for information exchange between database qu ...