Recoupling of heteronuclear dipolar interactions in solid state magic-angle spinning NMR by simultaneous frequency and amplitude modulation
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A magic angle spinning (MAS) NMR technique to transfer polarization from protons to a specific set of the C-13 spins is introduced for the study of biomolecular samples in the solid-state. Ultrafast (>60 kHz) MAS and low irradiation rf fields are used to a ...
We show how direct spectral optimisation can be used to provide significantly improved resolution for proton NMR spectroscopy in the solid state. We describe the design of new continuous phase modulated schemes for proton-proton homonuclear dipolar decoupl ...
The envelopes of spin-echo amplitudes obtained with trains of multiple refocusing pulses are normally modulated by homonuclear scalar couplings. Echo modulations make it difficult to determine transverse relaxation rate constants R2. Provided that the puls ...
A method for heteronuclear decoupling in fast magic-angle spinning NMR measurements comprises application of a decoupling RF-pulse sequence with a decoupling-field amplitude 1⁄2 1 I on spins of a first nucleus and of an excitation pulse on spins of a secon ...
The work presented here aims at understanding the performance of phase modulated heteronuclear decoupling sequences such as Cosine Modulation or Two Pulse Phase Modulation. To that end we provide an analytical description of the intrinsic behavior of Cosin ...
Since many biological processes occur on the μs to ms time scale, internal dynamics on that time scale may well be related to biological functionality. The characterization of internal dynamics is thus an important issue to improve our understanding of the ...
We report the development of the frequency-modulation (FM) method for measuring electron spin resonance (ESR) absorption in the 210- to 420 GHz frequency range. We demonstrate that using a high-frequency ESR spectrometer without resonating microwave compon ...
(Figure Presented) Chemical shifts of protons can report on metabolic transformations such as the conversion of choline to phosphocholine. To follow such processes in vivo, magnetization can be enhanced by dynamic nuclear polarization (DNP). We have hyperp ...
We propose a new scheme for heteronuclear decoupling designed for fast magic-angle spinning (MAS), dubbed phase-inverted supercycled sequence for attenuation of rotary resonance (PISSARRO). Its efficiency compares favourably with CW, TPPM, SPINAL and XiX d ...
In magic angle spinning solid-state NMR, the homonuclear J-couplings between pairs of spin-1/2 nuclei may be determined by studying the modulation of the spin echo induced by a pi-pulse, as a function of the echo duration. We present the theory of J-induce ...