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The octanol/water partition coefficient, logP, is one of the most important physico-chemical parameters for the development of new metal-based anticancer drugs with improved pharmacokinetic properties. This study addresses an issue with the absence of publ ...
This article presents a computational design methodology that integrates generative (architectural) and analytical (engineering) procedures into a simultaneous design process. By combining shape grammars and graphic statics, the proposed methodology enable ...
In this case study, we apply the architecture-based design approach to the control software of the CubETH satellite. Architectures are a means for ensuring global coordination properties and thus, achieving correctness of complex systems by construction. T ...
Four numerical codes are employed to investigate the dynamics of scrape-off layer filaments in tokamak relevant conditions. Experimental measurements were taken in the MAST device using visual camera imaging, which allows the evaluation of the perpendicula ...
The Mainstreaming Migration into Local Development project (MiDL) was launched in 2015 by UNDP Moldova in collaboration with the State Chancellery of the Government of Moldova, with financial support from the Swiss Agency for Development and Cooperation (S ...
Although nanoparticles research is ongoing since more than 30 years, the development of methods and standard protocols required for their safety and efficacy testing for human use is still in development. The review covers questions on toxicity, safety, ri ...
In order to tackle the challenges related to natural resources, the European Union has launched the flagship initiative "Resource Efficient Europe", which aims at reducing use of resources and improving the efficiency of their use. Other policy initiatives ...
Villigen PSI, World Resources Forum, printed by Paul Scherrer Institute2015
The teaching of architecture at the School of Architecture and Design at the Pontifical Catholic University of Valparaiso (the Valparaiso School) has very often been described as ‘very unusual’. One of the most exceptional and most often remarked upon aspe ...
The present work is the first of a series of papers aiming at a coherent and unified development of the thermodynamics of metabolism and the rationalization of feasibility analysis of metabolic pathways. The focus in this part is on high-level quantum chem ...
Why do chaperones need ATP hydrolysis to help proteins reach their native, functional states? In this review, we highlight the most recent experimental and theoretical evidences suggesting that ATP hydrolysis allows molecular chaperones to escape the bound ...