Molecular properties of fibrin-based matrices for promotion of angiogenesis in vitro
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Most tissue engineering approaches include the delivery of reparative cells to a damaged host tissue. Generally these cells are sought to be of a stem cell character since they retain a high potential for proliferation and differentiation into diverse phen ...
We show that synthetic three-dimensional (3D) matrix metalloproteinase (MMP)-sensitive poly(ethylene glycol) (PEG)-based hydrogels can direct differentiation of pluripotent cardioprogenitors, using P19 embryonal carcinoma (EC) cells as a model, along a car ...
Most eigenvalue problems arising in practice are known to be structured. Structure is often introduced by discretization and linearization techniques but may also be a consequence of properties induced by the original problem. Preserving this structure can ...
The rigidity function of a matrix is defined as the minimum number of its entries that need to be changed in order to reduce the rank of the matrix to below a given parameter. Proving a strong enough lower bound on the rigidity of a matrix implies a nontri ...
In this thesis, we deal with binet matrices, an extension of network matrices. The main result of this thesis is the following. A rational matrix A of size n×m can be tested for being binet in time O(n6m). If A is binet, our algorithm outputs a nonsingular ...
The evaluation of colorimetric films for the detection of low concentrations of gaseous ammonia in a waveguide configuration is presented. They were composed of a pH indicator selective to NH3 embedded in a polymeric matrix and deposited on an optical wave ...
Interstitial fluid flow, critical for macromolecular transport, was recently shown to drive fibroblast differentiation and perpendicular cell and matrix alignment in 3D collagen cultures. Here we explore the mechanisms underlying this flow-induced cell and ...
We report absorption spectra for Ag7, Ag9, and Ag11 in an argon matrix grown at a temperature of 28 K and compare them with previous spectra of the same species measured in matrices of argon grown at lower temperatures as well as in neon matrices. We discu ...
Poly(lactide-co-glycolide) (PLGA) scaffolds have been successfully used in bone tissue engineering, with or without hydroxyapatite (HA) and with a macroporosity given either by simple PLGA sphere packaging and/or by leaching out NaCI. The objective of this ...
In vitro endothelial cell organization into capillaries is a long standing challenge of tissue engineering. We recently showed the utility of low level interstitial flow in guiding the organization of endothelial cells through a 3-D fibrin matrix-containin ...