Switchable reactivity: the site-selective functionalization of trifluoromethyl-substituted pyrazoles
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Triazenes are valuable compounds in organic chemistry and numerous applications have been reported. Furthermore, triazenes have been investigated extensively as potential antitumor drugs. Here, we describe a new method for the synthesis of triazenes. The p ...
Carbon-carbon bond forming reactions are among the most important and useful methods for organic synthesis. During the last years, significant progress has been made in this field. Whereas many catalysts were developed for the coupling of aryl, alkenyl, an ...
2-, 3- and 4-substituted fluorobenzenes and 5-substituted 1,3-difluorobenzenes were metalated with sec-butyllithium (LIS) and with lithium 2,2,6,6-tetramethylpiperidide (LiTMP) under irreversible conditions in order to determine the rates of reaction relat ...
This report describes a full study of the gold-catalyzed direct alkynylation of indoles, pyrroles, and thiophenes using alkynyl hypervalent iodine reagents, especially the study of the structural requirements of alkynyl benziodoxolones for an efficient ace ...
The cyclopentane scaffold has attracted much attention due to its ubiquity in numerous bioactive natural products such as prostaglandins and polyquinanes. However, despite a plethora of available procedures to access this motif, a lack of methods that riva ...
Given a fiber bundle of GKM spaces, pi: M -> B, we analyze the structure of the equivariant K-ring of M as a module over the equivariant K-ring of B by translating the fiber bundle, pi, into a fiber bundle of GKM graphs and constructing, by combinatorial t ...
Easy does it: The unique properties of benziodoxolone alkynyl periodinane 1 and gold catalysts have allowed the development of a high yielding, operationally simple (room temperature, no dry solvents or inert conditions, commercially available catalyst) re ...
Let G be a finite group, let p be a prime number, and let K be a field of characteristic 0 and k be a field of characteristic p, both large enough. In this note, we state explicit formulae for the primitive idempotents of the ring of p-permutation kG-modul ...
We study classes of modules over a commutative ring which allow to do homological algebra relative to such a class. We classify those classes consisting of injective modules by certain subsets of ideals. When the ring is Noetherian the subsets are precisel ...
The development of efficient synthetic methodologies is crucial to access complex molecules in an economic, eco-friendly and safe way. The reversal of the intrinsic reactivity of functional groups, called Umpolung, allows alternative synthetic strategies a ...