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Immobilized pH Gradient Gel Cell To Study the pH Dependence of Drug Lipophilicity

Related publications (46)

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Assessment of lifestyle changes for greenhouse gas emissions reduction in Switzerland

In light of the climate change crisis, this study looks at what actions can be done by individuals in Switzerland to reduce their carbon footprint. A total of 40 actions spanned over 6 areas of consumption (food, housing, mobility, at home leisure activiti ...

2020

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We discuss grand canonical simulations based on density-functional theory to study the thermodynamic properties of electrochemical interfaces of metallic electrodes in aqueous environments. Water is represented using implicit solvation, here via the self-c ...

AMER INST PHYSICS2019

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Butyronitrile is an organic solvent stable enough to be used in photochemical reactions at liquid/liquid interfaces. However, it provides a rather short polarisation window making the analysis of ion transfer across the water|butyronitrile interface challe ...

2019

2D nanopores: fabrication, energy harvesting and field-effect sensing

Michael Graf

Solid-state nanopores are man-made, nano-sized openings in membranes separating two chambers containing an electrolyte solution. When applying an electric field across the membrane, the nanopore provides the only path for mobile ions to pass from one side ...

EPFL2019

Patchy Surfaces

Nikolaos Nianias

Tailoring solid surfaces attracts a number of technological and scientific interest with numerous applications. One method to modify a solid surface is via the formation of a molecular film. The adsorbed molecules assemble spontaneously (self assemble) for ...

EPFL2018

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A target plate for enhanced matrix-assisted laser desorption/ionization mass spectrometry (MALDI MS) analysis of intact biological entities. The target plate comprises an electrically conductive substrate (1) covered at least partially with immobilised pho ...

2018

Free energies play a central role in many descriptions of equilibrium and non-equilibrium properties of solids. Continuum partial differential equations (PDEs) of atomic transport, phase transformations and mechanics often rely on first and second derivati ...

Elsevier2017

Membranes, composed of a variety of lipids and other biomolecules, mediate signaling processes between cells and their aqueous environment. To fulfill this function, membranes can vary their composition leaflet-specific and thus alter their surface propert ...

EPFL2017

Rationalizing the In Vivo Degradation of Metal-on-Metal Artificial Hip Joints Using Tribocorrosion Concepts

Stefano Mischler, Shoufan Cao

In this study, the in vivo degradation of metal-on-metal (MoM) artificial hip joints was assessed based on the present state of the art concepts of tribocorrosion. A recently developed tribocorrosion model, based on the combination of mechanical and corros ...

Natl Assoc Corrosion Eng2017

Migration of surface excitations in highly-excited nanosystems probed by intense resonant XUV radiation

Marcel Drabbels

Ionization dynamics of resonantly excited helium nanodroplets have been studied by intense XUV light. By doping the nanodroplets with atoms that either attach to the surface or submerge into the center of the droplet, one can study the dynamics of excitati ...

2015