Ion physics and technologies for the trace element analysis
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Mass spectrometry (MS) is an essential detection tool in bioanalytical chemistry owing to its exceptional selectivity and sensitivity, paired with rapid analyte identification and quantification. In this thesis, two classical MS and a newly developed ioniz ...
Accumulation of spectra is a common approach for improvement of the signal-to-noise ratio (SNR) in mass spectrometry. However, severe degradation of the overall spectrum can occur if some individual mass spectra, affected by peak broadening, are included i ...
Mass spectrometry is a powerful analytical technique, which has become invaluable across a wide range of scientific fields, such as "omics" sciences (e.g., proteomics), doping control and forensic sciences, drug development, environmental analysis, geologi ...
The present invention relates to a method and device for measuring m/z ratios of ions in ion cyclotron resonance (ICR) mass spectrometry. The described ion traps for ICR mass spectrometry are distinct from the previous configurations by having one or many ...
Field Asymmetric IonMobility Spectrometry (FAIMS) is a very promising technique for chemical detection. FAIMS systems are portable, highly sensitive, relatively inexpensive and can work at atmospheric conditions. These attributes make it a very desirable t ...
Hydrogels have been used extensively in bioengineering as artificial cell culture supports. Investigation of the interrelationship between cellular response to the hydrogel and its chemistry ideally requires methods that allow characterization without labe ...
A method of analyzing molecules enabling chemical, structural and isomeric or conformational identification of the molecules, particularly in a stream from a chromatographic separation, comprising: generating ions from a sample of molecules to be analyzed; ...
Highly ionic beams of several hundred microampere per squared centimeter have been measured from porous glass ionic liquid electrospray sources fabricated using a conventional mill. The thrust output from three prototype devices, two emitting the ionic liq ...
American Institute of Aeronautics and Astronautics2016
A target plate for enhanced matrix-assisted laser desorption/ionization mass spectrometry (MALDI MS) analysis of intact biological entities. The target plate comprises an electrically conductive substrate (1) covered at least partially with immobilised pho ...
A method has been presented for accounting for ion fragmentation that occurs within the nonzero field of an ionic electrospray thruster. Given the complexities associated with direct thrust measurements, indirect means (and time-of-flight (TOF) in particul ...
American Institute of Aeronautics and Astronautics2015