Implantable blood pressure monitor

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Validation of a Non-invasive Inverse Problem-Solving Method for Stroke Volume

Nikolaos Stergiopoulos, Georgios Rovas, Vasiliki Bikia, Stamatia Zoi Pagoulatou, Emma Marie Roussel

Stroke volume (SV) is a major biomarker of cardiac function, reflecting ventricular-vascular coupling. Despite this, hemodynamic monitoring and management seldomly includes assessments of SV and remains predominantly guided by brachial cuff blood pressure ...

FRONTIERS MEDIA SA2022

p-Aminobenzamidine attenuates cardiovascular dysfunctions in spontaneously hypertensive rats

Nikolaos Stergiopoulos, Fabiana Pereira Da Costa Fraga, Allancer Divino De Carvalho Nunes

Aims:Diminazene aceturate, a putative ACE2 activator, is susceptible to cleavage resulting in the formation of paminobenzamidine (PAB). This study aimed to investigate the effects of PAB in addressing cardiovascular dysfunctions in spontaneously hypertensi ...

PERGAMON-ELSEVIER SCIENCE LTD2022

Implanted System for Orthostatic Hypotension in Multiple-System Atrophy

Grégoire Courtine, Léonie Asboth, Jocelyne Bloch, Robin Jonathan Demesmaeker, Jordan Squair, Grégory Didier Dumont, Nicolas Hankov, Sergio Daniel Hernandez, Suje Amir, Maxime Berney

Orthostatic hypotension is a cardinal feature of multiple-system atrophy. The upright posture provokes syncopal episodes that prevent patients from standing and walking for more than brief periods. We implanted a system to restore regulation of blood press ...

MASSACHUSETTS MEDICAL SOC2022

Assessment of Stiffness of Large to Small Arteries in Multistage Renal Disease Model: A Numerical Study

Nikolaos Stergiopoulos, Vasiliki Bikia, Patrick Segers

Arterial stiffness (AS), as assessed via pulse wave velocity (PWV), is a major biomarker for cardiovascular risk assessment in patients with chronic kidney disease (CKD). However, the mechanisms responsible for the changes in PWV in the presence of kidney ...

FRONTIERS MEDIA SA2022

Cardiovascular monitoring system

Marco Mattavelli, Catherine Dehollain, Diego Ruben Barrettino, Kerim Türe, Mustafa Besirli

A cardiovascular monitoring system for measuring at least cardiac output comprises an implantable unit (2) configured for placement in a section of artery of a patient and a portable external unit (1) configured for mounting against or close to a patient's ...

2022

An Energy-Efficient Bridge-to-Digital Converter for Implantable Pressure Monitoring Systems

Marco Mattavelli, Catherine Dehollain, Diego Ruben Barrettino, Kerim Türe, Mustafa Besirli, Franco Maloberti

This paper presents an energy-efficient, duty-cycled, and spinning excitation bridge-to-digital converter (BDC) designed for implantable pressure sensing systems. The circuit provides the measure of the pulmonary artery pressure that is particularly releva ...

2022

Improving the Accuracy of Fracture Toughness Measurement in Burst Experiments

Guanyi Lu, Yixuan Zhang

Experimental studies suggest that the fracture toughness of rocks increases with the confining pressure. Among many methods to quantify this dependency, a so-called burst experiment (Abou-Sayed, 1978) may be the most widely applied in practice. Its thick w ...

SPRINGER WIEN2022

Overflow pressure characterization in lined plunge pools for slab sizing

Giovanni De Cesare, Pedro Filipe De Almeida Manso, Francisca Marco Cutillas

This study presents an experimental work on dynamic pressures at the bottom of a lined plunge pool that receives overflow rectangular impinging jets and aims at improving the design criteria for pool slabs. The experiments were conducted in a fairly large ...

International Association for Hydro-Environment Engineering and Research (IAHR)2022

Temperature- and pressure-dependence of the hydrogen bond network in plastic ice VII

Livia Eleonora Bove Kado, Umbertoluca Ranieri, Maria Rescigno

We model, via classical molecular dynamics simulations, the plastic phase of ice VII across a wide range of the phase diagram of interest for planetary investigations. Although structural and dynamical properties of plastic ice VII are mostly independent o ...

AIP Publishing2022

On the assessment of arterial compliance from carotid pressure waveform

Nikolaos Stergiopoulos, Georgios Rovas, Vasiliki Bikia, Stamatia Zoi Pagoulatou, Patrick Segers

In a progressively aging population, it is of utmost importance to develop reliable, noninvasive, and cost-effective tools to estimate biomarkers that can be indicative of cardiovascular risk. Various pathophysiological conditions are associated to changes ...

AMER PHYSIOLOGICAL SOC2021

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