Mutually antagonistic effects of corticosterone and prolactin on rat lymphocyte proliferation
Graph Chatbot
Chat with Graph Search
Ask any question about EPFL courses, lectures, exercises, research, news, etc. or try the example questions below.
DISCLAIMER: The Graph Chatbot is not programmed to provide explicit or categorical answers to your questions. Rather, it transforms your questions into API requests that are distributed across the various IT services officially administered by EPFL. Its purpose is solely to collect and recommend relevant references to content that you can explore to help you answer your questions.
Despite their limited proliferation capacity, regulatory T cells (T(regs)) constitute a population maintained over the entire lifetime of a human organism. The means by which T(regs) sustain a stable pool in vivo are controversial. Using a mathematical mod ...
Life Cycle Assessment (LCA) is a tool developed to evaluate the environmental impact of a product or a system. After a decade of research in the LCA field, significant progress has been achieved but methodologies for the assessment of toxicological impacts ...
The protooncogene MYC has been implicated in both the proliferation and programmed cell death of lymphoid cells, and in the genesis of lymphoid tumors. Here, we report that overexpression of MYC, as found in many lymphomas, can break immune tolerance. Mice ...
Steroid receptor coactivator 3 (SRC-3/ACTR/AIB-1/pCIP/RAC3/TRAM-1) is a member of the p160 family of nuclear receptor coactivators that plays an important role in mammary gland growth, development, and tumorigenesis. We show that deletion of SRC-3 gene dec ...
The decision-making process regarding drug dose, regularly used in everyday medical practice, is critical to patients’ health and recovery. It is a challenging process, especially for a drug with narrow therapeutic ranges, in which a medical doctor decides ...
The neurotransmitter noradrenaline (NA) plays a pivotal role in immune regulation. Here we used the selective neurotoxin N-(2-chloroethyl)-N-ethyl-2-bromobenzylamine (DSP-4) to investigate the impact of central NA depletion on cytokine production by spleni ...
The immune system and iron availability are intimately linked as appropriate iron supply is needed for cell proliferation, while excess iron, as observed in hemochromatosis, may reduce subsets of lymphocytes. We have tested the effects of a ferritin H gene ...
Although canonical Notch signaling regulates multiple hematopoietic lineage decisions including T cell and marginal zone B cell fate specification, the downstream molecular mediators of Notch function are largely unknown. We showed here that conditional in ...
This thesis is a contribution to multivariate extreme value statistics. The tail of a multivariate distribution function is characterized by its spectral distribution, for which we propose a new semi-parametric model based on mixtures of Dirichlet distribu ...
The immune system has to decide on the reaction it will perform when it encounters a pathogen for the first time. The decision is based on the context in which the pathogen is presented and the signals it receives from the innate immune system. Thereafter ...