System for closed loop control of autonomic function

A neuromodulation system (10,110) is disclosed, especially a neurostimulation system (10,110), for treating a patient, especially for enhancing at least one autonomous function such a blood circulation and/or respiration, wherein the system comprises • - at least one signal input module (12,112), which is configured to receive at least one or more signals being indicative for blood circulation, especially being indicative for pulse and/or blood pressure, • - at least one control module (14,114), wherein the control module (14, 114) is connected to the signal input module (12,112), wherein the control module (14, 114) is configured to adapt the neurostimulation provided by the neuromodulation system (10,110) on the basis of the signal(s) received by the signal input module (12,112).