Unit
The Ablasser Lab at EPFL focuses on understanding how the cells of the immune system detect pathogens and the mechanisms underlying host defense. Their research delves into the intracellular recognition of pathogen-derived molecular patterns, signaling events, and the physiological functions of these pathways. The lab's work on the cGAS-STING pathway sheds light on how cells sense DNA as a danger signal, leading to an innate immune response. By studying the molecular rules governing this pathway's activity, they aim to develop new insights for innovative medicines.
Jacques Fellay, Flavia Aurelia Shoko Hodel