Concept
Alloprégnanolone
Publications associées (19)
Hypothalamic pregnenolone mediates recognition memory in the context of metabolic disorders
Maria del Carmen Sandi Perez, Ioannis Zalachoras, Sara Ramirez Flores
Obesity and type 2 diabetes are associated with cognitive dysfunction. Because the hypothalamus is implicated in energy balance control and memory disorders, we hypothesized that specific neurons in this brain region are at the interface of metabolism and ...
Elsevier2022MondoA regulates gene expression in cholesterol biosynthesis-associated pathways required for zebrafish epiboly
Cédric Gobet, Frédéric Bruno Martin Gachon, Benjamin Dieter Weger, Meltem Weger
The glucose-sensing Mondo pathway regulates expression of metabolic genes in mammals. Here, we characterized its function in the zebrafish and revealed an unexpected role of this pathway in vertebrate embryonic development. We showed that knockdown of mond ...
2020Significant Molecular and Systemic Adaptations after Repeated Sprint Training in Hypoxia
Jean-Marc Vesin, Grégoire Millet
While intermittent hypoxic training (IHT) has been reported to evoke cellular responses via hypoxia inducible factors (HIFs) but without substantial performance benefits in endurance athletes, we hypothesized that repeated sprint training in hypoxia could ...
Public Library of Science2013Paracrine signaling by progesterone
Cathrin Brisken, Renuga Devi Rajaram
Steroid hormones coordinate and control the development and function of many organs and are implicated in many pathological processes. Progesterone signaling, in particular, is essential for several important female reproductive functions. Physiological ef ...
Elsevier2012Role of canonical Wnt signaling in mammary gland development
The female reproductive hormones estrogens, progesterone, and prolactin control postnatal breast development and are important to breast carcinogenesis. In particular, exposure to progesterone is tightly linked to breast cancer risk. Using the mouse as a m ...
EPFL2010