Publications associées à Synapomorphie

A Framework for Autonomic Computing for In Situ Imageomics

In situ imageomics is a new approach to study ecological, biological and evolutionary systems wherein large image and video data sets are captured in the wild and machine learning methods are used to infer biological traits of individual organisms, animal ...

The Institute of Electrical and Electronics Engineers, Inc2023

Back-to-Africa introductions of Mycobacterium tuberculosis as the main cause of tuberculosis in Dar es Salaam, Tanzania

Jacques Fellay, Zhi Ming Xu

In settings with high tuberculosis (TB) endemicity, distinct genotypes of the Mycobacterium tuberculosis complex (MTBC) often differ in prevalence. However, the factors leading to these differences remain poorly understood. Here we studied the MTBC populat ...

PUBLIC LIBRARY SCIENCE2023

Statistical inference in ensemble modeling of cellular metabolism

Vassily Hatzimanikatis, Marc-Olivier Boldi, Tuure Eelis Hameri

Kinetic models of metabolism can be constructed to predict cellular regulation and devise metabolic engineering strategies, and various promising computational workflows have been developed in recent years for this. Due to the uncertainty in the kinetic pa ...

2019

Optimization of Conformational Dynamics in an Epistatic Evolutionary Trajectory

Luciano Andres Abriata

The understanding of protein evolution depends on the ability to relate the impact of mutations on molecular traits to organismal fitness. Biological activity and robustness have been regarded as important features in shaping protein evolutionary landscape ...

Oxford Univ Press2016

Inferring the Evolutionary History of Primate microRNA Binding Sites: Overcoming Motif Counting Biases

Jeffrey David Jensen, Feng Gao

The first microRNAs (miRNAs) were identified as essential, conserved regulators of gene expression, targeting the same genes across nearly all bilaterians. However, there are also prominent examples of conserved miRNAs whose functions appear to have shifte ...

Oxford Univ Press2014

Convergent evolution of complex regulatory landscapes and pleiotropy at Hox loci

Denis Duboule, Fabrice Daniel Darbellay, Nicolas Lonfat

Hox genes are required during the morphogenesis of both vertebrate digits and external genitals. We investigated whether transcription in such distinct contexts involves a shared enhancer-containing landscape. We show that the same regulatory topology is u ...

Amer Assoc Advancement Science2014

Biomineralization in living hypercalcified demosponges: Toward a shared mechanism?

Melany Melissa Gilis

Massive skeletons of living hypercalcified sponges, representative organisms of basal Metazoa, are uncommon models to improve our knowledge on biomineralization mechanisms and their possible evolution through time. Eight living species belonging to various ...

Academic Press Inc Elsevier Science2013

Can survival prediction be improved by merging gene expression data sets?

Philipp Bucher, Haleh Yasrebi

BACKGROUND: High-throughput gene expression profiling technologies generating a wealth of data, are increasingly used for characterization of tumor biopsies for clinical trials. By applying machine learning algorithms to such clinically documented data set ...

Public Library of Science2009

Ribosomal RNA Genes Challenge the Monophyly of the Hyalospheniidae (Amoebozoa: Arcellinida)

Edward Mitchell, Mariusz Lamentowicz, Enrique Lara, Thierry Jean Heger

To date only five partial and two complete SSU rRNA gene sequences are available for the lobose testate amoebae (Arcellinida). Consequently, the phylogenetic relationships among taxa and the definition of species are still largely dependant on morphologica ...

2008

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Synapomorphie

A Framework for Autonomic Computing for In Situ Imageomics

Back-to-Africa introductions of Mycobacterium tuberculosis as the main cause of tuberculosis in Dar es Salaam, Tanzania

Statistical inference in ensemble modeling of cellular metabolism

Optimization of Conformational Dynamics in an Epistatic Evolutionary Trajectory

Tetrapod axial evolution and developmental constraints; Empirical underpinning by a mouse model

Inferring the Evolutionary History of Primate microRNA Binding Sites: Overcoming Motif Counting Biases

Convergent evolution of complex regulatory landscapes and pleiotropy at Hox loci

Biomineralization in living hypercalcified demosponges: Toward a shared mechanism?

Can survival prediction be improved by merging gene expression data sets?

Ribosomal RNA Genes Challenge the Monophyly of the Hyalospheniidae (Amoebozoa: Arcellinida)

Graph Chatbot

Chattez avec Graph Search

Statistical inference in ensemble modeling of cellular metabolism

Biomineralization in living hypercalcified demosponges: Toward a shared mechanism?

Tetrapod axial evolution and developmental constraints; Empirical underpinning by a mouse model

Can survival prediction be improved by merging gene expression data sets?

Back-to-Africa introductions of Mycobacterium tuberculosis as the main cause of tuberculosis in Dar es Salaam, Tanzania

Optimization of Conformational Dynamics in an Epistatic Evolutionary Trajectory

Inferring the Evolutionary History of Primate microRNA Binding Sites: Overcoming Motif Counting Biases

Convergent evolution of complex regulatory landscapes and pleiotropy at Hox loci

Ribosomal RNA Genes Challenge the Monophyly of the Hyalospheniidae (Amoebozoa: Arcellinida)