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Publications associées (69)

Bacterial strategies to overcome insect defences

Recent genetic and molecular analyses have revealed how several strategies enable bacteria to persist and overcome insect immune defences. Genetic and genomic tools that can be used with Drosophila melanogaster have enabled the characterization of the path ...

2008

Characterization of APOBEC3G binding to 7SL RNA

Didier Trono, Bastien Mangeat

ABSTRACT: Human APOBEC3 proteins are editing enzymes that can interfere with the replication of exogenous retroviruses such as human immunodeficiency virus (HIV), hepadnaviruses such as hepatitis B virus (HBV), and with the retrotransposition of endogenous ...

2008

Modeling an evolutionary conserved circadian cis-element

Felix Naef, Eric Paquet, Guillaume Rey

Circadian oscillator networks rely on a transcriptional activator called CLOCK/CYCLE (CLK/CYC) in insects and CLOCK/BMAL1 or NPAS2/BMAL1 in mammals. Identifying the targets of this heterodimeric basic-helix-loop-helix (bHLH) transcription factor poses chal ...

Public Library of Science2008

From online experiments to smart devices

Denis Gillet, Christophe Salzmann

Online experiments have been available for more than a decade. The integration of online experiments to collaborative environments is more recent. The wealth of client application/environments, the versatility of possible interaction protocols/technologies ...

2008

Genome plasticity of BCG and impact on vaccine efficacy

Stewart Cole

To understand the evolution, attenuation, and variable protective efficacy of bacillus Calmette-Guérin (BCG) vaccines, Mycobacterium bovis BCG Pasteur 1173P2 has been subjected to comparative genome and transcriptome analysis. The 4,374,522-bp genome conta ...

2007

Measurements of branching fractions and q2 distributions for B → π ℓ ν and B → ρ ℓ ν decays with B → D(*) ℓ ν decay tagging

Olivier Schneider, Aurelio Bay, Stewart Cole, Mingkui Wang, Chao Wang, Tagir Aushev, Lei Zhang, Vladislav Balagura, Jing Li

We report measurements of the charmless semileptonic decays B0 → π- / ρ- ℓ+ ν and B+ → π0 / ρ0 ℓ+ ν, based on a sample of 2.75 × 108B over(B, ̄) events collected at the Υ{hooked} (4 S) resonance with the Belle detector at the KEKB e+ e- asymmetric collider ...

2007

Mining gene sets for measuring similarities

Giovanni De Micheli, Luca Benini

In recent years, the development of high throughput devices for the massive parallel analyses of genomic data has lead to the generation of large amount of new biological evidences and has triggered the proliferation of data mining algorithms for the extra ...

2006

Computational Identification of MicroRNAs and Their Targets

Giovanni De Micheli

One of the most important advances in biology in recent years may be the discovery of RNAs that can regulate gene expression. As one kind of such functional noncoding RNAs, microRNAs (miRNAs) forma class of endogenous 19–23-nucleotide RNAs that can have im ...

Wiley-Blackwell2006

Overview of recent European materials R&D activities related to ITER

An overview is given of the wide range of activities contained within recent R&D being performed within Europe on In-vessel materials for structural, heat sink and plasma facing purposes for ITER. The effect of creep-fatigue interaction on the fatigue life ...

2004

Colinearity loops out

Denis Duboule

Modulation of chromatin structure has long been proposed to underlie the colinear regulation of Hox genes during animal development. In a recent paper, Chambeyron and Bickmore explore this possibility in retinoic acid-induced ES cells. They show that, whil ...

2004

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