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We present dyngen, a multi-modal simulation engine for studying dynamic cellular processes at single-cell resolution. dyngen is more flexible than current single-cell simulation engines, and allows better method development and benchmarking, thereby stimul ...
Proteins are fundamental components in biological systems and crucial for a variety of biological functions. Over the last decades, significant progress in structural biology has facilitated the study of proteins and their interactions with molecular partn ...
We present Bistable Auxetic Surface Structures, a novel deployable material system based on optimized bistable auxetic cells. Such a structure can be flat-fabricated from elastic sheet material, then deployed towards a desired double-curved target shape by ...
Due to the growing pressure of digitization and open access demands, cultural institutions are increasingly presenting their collections in digital space. Dealing with this constantly growing amount of data poses a major challenge, especially with regard t ...
Engineering biosensors that sensitively recognize specific biomolecules and trigger functional cellular responses is a holy grail of diagnostics and synthetic cell biology. Biosensor design approaches have mostly focused on binding structurally well-define ...
James (Jim) Morgan was a leading figure in the field of environmental science and engineering. He championed the application of chemistry in the study of the environment and the design and optimization of environmental treatment processes. Jim influenced t ...
In this paper we study Weingarten surfaces and explore their potential for fabrication-aware design in freeform architecture. Weingarten surfaces are characterized by a functional relation between their principal curvatures that implicitly defines approxim ...
An assembly refers to a collection of parts joined together to achieve a specific form and/or functionality. Designing assemblies is a non-trivial task as a slight local modification on a part's geometry or its joining method could have a global impact on ...
Globalization, outsourcing and cost optimization have all contributed to increased supply chain vulnerability, yet our understanding of effective mitigation strategies remains limited. In our research, we study the effects of disruptions on supply chain ne ...
An assembly refers to a collection of parts joined together to achieve a specific form and/or functionality. Designing assemblies is a non-trivial task as a slight local modification on a part's geometry or its joining method could have a global impact on ...