Concept

Mélanopsine

Publications associées (42)

RBP-Jκ-dependent Notch signaling enhances retinal pigment epithelial cell proliferation in transgenic mice

Freddy Radtke, Friedrich Beermann, Iraz Toprak Aydin

The Notch signaling pathway is an ubiquitous cell-cell interaction mechanism, which is essential in controlling processes like cell proliferation, cell fate decision, differentiation or stem cell maintenance. Recent data have shown that Notch signaling is ...

Nature Publishing Group2011

Genetic Reactivation of Cone Photoreceptors Restores Visual Responses in Retinitis pigmentosa

Didier Trono, Anna Claire Groner

Retinitis pigmentosa refers to a diverse group of hereditary diseases affecting two million people worldwide that lead to incurable blindness. As a common pathology, rod photoreceptors die early whereas light-insensitive, morphologically altered cone photo ...

American Association for the Advancement of Science2010

A conserved protonation-induced switch can trigger "ionic lock" formation in adrenergic receptors

Ursula Röthlisberger, Ivano Tavernelli, Marilisa Neri, Stefano Vanni

The mechanism of signal transduction in G-protein-coupled receptors (GPCRs) is a crucial step in cell signaling. However, the molecular details of this process are still largely undetermined. Carrying out submicrosecond molecular dynamics simulations of be ...

Elsevier2010

Combined inhibition of Cdk5 and ROCK additively increase cell survival, but not the regenerative response in regenerating retinal ganglion cells

CNS regeneration is limited by lesion-induced neuronal apoptosis and an environment inhibiting axonal elongation. Inhibition of ROCK has been previously shown to promote regeneration in retinal ganglion cells (RGC) whereas Cdk5 inhibition mainly promoted s ...

2009

Daylight Exposure and Circadian Efficiency in Office Rooms Equipped with Anidolic Daylighting Systems

Jean-Louis Scartezzini, Mirjam Münch, Friedrich Linhart

Anidolic Daylighting Systems (ADS) typically reduce the daylight flux reaching an office room‟s window section and increase it in the rear of the room. They offer interesting possibilities for the combination of comfortable daylighting and highly energy-ef ...

EPFL2009

Ultrathin four-reflection imager

We present the design and experimental demonstration of an ultrathin four-reflection imager. The F/1.15 prototype imager achieves a focal length of 18.6 mm in a track length of just 5.5 mm, providing a 17° field of view over 1.92 megapixels of a color imag ...

2009

NR2E3 Mutations in Enhanced S-Cone Sensitivity Syndrome (ESCS), Goldmann-Favre Syndrome (GFS), Clumped Pigmentary Retinal Degeneration (CPRD), and Retinitis Pigmentosa (RP)

Pascal Escher

NR2E3, also called photoreceptor-specific nuclear receptor (PNR), is a transcription factor of the nuclear hormone receptor superfamily whose expression is uniquely restricted to photoreceptors. There, its physiological activity is essential for proper rod ...

2009

Vibrational properties of rare-earth nitrides: Raman spectra and theory

Simon Granville, Harry Joseph Trodahl

Raman spectra are presented for the rare-earth nitrides SmN, GdN, DyN, ErN, and LuN measured with 633 and 514 nm excitation wavelengths and at temperatures above and below the Curie temperature. Frozen-phonon calculations are presented for the phonons at G ...

2009

A Model of Retinal Local Adaptation for the Tone Mapping of Color Filter Array Images

Sabine Süsstrunk, Laurence Meylan

We present a tone mapping algorithm that is derived from a model of retinal processing. Our approach has two major improvements over existing methods. First, tone mapping is applied directly on the mosaic image captured by the sensor, analogue to the human ...

2007

Parameterization of cloud droplet formation in large-scale models: Including effects of entrainment

Athanasios Nenes

This work offers for the first time a comprehensive parameterization suitable for large-scale models which is robust, computationally efficient, and from first principles links chemical effects, aerosol heterogeneity and entrainment with cloud droplet form ...

Blackwell Publishing Ltd2007

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