Publications associées à Quotient d'encéphalisation

Redox and Immune Signaling in Schizophrenia: New Therapeutic Potential

Redox biology and immune signaling play major roles in the body, including in brain function. A rapidly growing literature also suggests that redox and immune abnormalities are implicated in neuropsychiatric conditions such as schizophrenia (SZ), bipolar d ...

OXFORD UNIV PRESS2023

A synchrotron X-ray imaging strategy to map large animal brains

Giorgio Margaritondo, Ying Chen

Mapping the large neural networks of animal and human brains is a fundamental but so far elusive task, because of the massive amount of data and the consequent prohibitively long image taking and processing times. We developed an effective strategy called ...

2020

Data-driven reconstruction of a point neuron mouse brain

Csaba Erö

In this work, we present a semi-automatic method to reconstruct a mouse whole-brain model at the point-neuron level by integrating a wide array of biological data. Our process has three parts: cell position and type assignment, connectivity mapping, and si ...

EPFL2018

Studying cyto and myeloarchitecture of the human cortex at ultra-high field with quantitative imaging: R1, R⁎2 and susceptibility

Rolf Gruetter, José Pedro Rebelo Ferreira Marques, Diana Khabipova

In this manuscript, the use of quantitative imaging at ultra-high field is evaluated as a mean to study cyto and myelo-architecture of the cortex. The quantitative contrasts used are the longitudinal relaxation rate (R1), apparent transverse relaxation rat ...

Elsevier2017

Progress towards in vivo brain (13)C-MRS in mice: Metabolic flux analysis in small tissue volumes

Rolf Gruetter, Bernard Lanz, Marta Lai

The combination of dynamic (13)C MRS data under infusion of (13)C-labeled substrates and compartmental models of cerebral metabolism enabled in vivo measurement of metabolic fluxes with a quantitative and distinct determination of cellular-specific activit ...

Elsevier2017

Decoding the mechanisms of gait generation in salamanders by combining neurobiology, modeling and robotics

Auke Ijspeert, Andrej Bicanski, Jérémie Knüsel

Vertebrate animals exhibit impressive locomotor skills. These locomotor skills are due to the complex interactions between the environment, the musculo-skeletal system and the central nervous system, in particular the spinal locomotor circuits. We are inte ...

Springer Berlin Heidelberg2013

How to Measure Cortical Folding from MR Images: a Step-by-Step Tutorial to Compute Local Gyrification Index

Jean-Philippe Thiran, Meritxell Bach Cuadra, Marie Schaer

Cortical folding (gyrification) is determined during the first months of life, so that adverse events occurring during this period leave traces that will be identifiable at any age. As recently reviewed by Mangin and colleagues2, several methods exist to q ...

2012

Congenital heart disease affects local gyrification in 22q11.2 deletion syndrome

Jean-Philippe Thiran, Meritxell Bach Cuadra, Marie Schaer

22q11.2 deletion syndrome (22q11.2DS) is a common genetic condition associated with cognitive and learning impairments. In this study, we applied a threedimensional method for quantifying gyrification at thousands of points over the cortical surface to ima ...

Wiley-Blackwell2009

Genes, Brain Development and Psychiatric Phenotypes in Velo-Cardio-Facial Syndrome

Marie Schaer

Velo-cardio-facial syndrome (VCFS) has been in the focus of intensive research over the last 15 years. The syndrome represents a homogeneous model for studying the effect of a decreased dosage of genes on the development of brain structure and function and ...

2008