Publications associées à ADN antisens

The effects of mitochondrial- and histone stress on the C. elegans transcriptome

The aim of this study was to explore whether mitochondrial- and histone stress cause any common changes in global gene expression. For this experiment, we performed RNA sequencing from control RNAi, cco-1 RNAi (mitochondrial stress) and his-3 RNAi (histone ...

EPFL Infoscience2017

Structural Features of the Box C/D snoRNP Pre-assembly Process Are Conserved through Species

Benjamin Marcel Daniel Rothé

Box C/D small nucleolar ribonucleoparticles (snoRNPs) support 2'-O-methylation of several target RNAs. They share a common set of four core proteins (SNU13, NOP58, NOP56, and FBL) that are assembled on different guide small nucleolar RNAs. Assembly of thes ...

Cell Press2016

Hotair Is Dispensible for Mouse Development

Denis Duboule, Anamaria Necsulea

Despite the crucial importance of Hox genes functions during animal development, the mechanisms that control their transcription in time and space are not yet fully understood. In this context, it was proposed that Hotair, a lncRNA transcribed from within ...

Public Library Science2016

Potential Direct Regulators of the Drosophila yellow Gene Identified by Yeast One-Hybrid and RNAi Screens

Bart Deplancke

The regulation of gene expression controls development, and changes in this regulation often contribute to phenotypic evolution. Drosophila pigmentation is a model system for studying evolutionary changes in gene regulation, with differences in expression ...

Genetics Society of America2016

A Large-Scale Functional Screen to Identify Epigenetic Repressors of Retrotransposon Expression

Didier Trono, Gabriela Ecco, Helen Mary Rowe

Deposition of epigenetic marks is an important layer of the transcriptional control of retrotransposons, especially during early embryogenesis. Krüppel-associated box domain zinc finger proteins (KRAB-ZFPs) are one of the largest families of transcription ...

2016

An experimental evaluation of drug-induced mutational meltdown as an antiviral treatment strategy

Jeffrey David Jensen, Matthieu Foll, Claudia Bank, Sebastian Matuszewski, Hyunjin Shim

The rapid evolution of drug resistance remains a critical public health concern. The treatment of influenza A virus (IAV) has proven particularly challenging, due to the ability of the virus to develop resistance against current antivirals and vaccines. He ...

Wiley-Blackwell2016

Growth control switch by a DNA-damage-inducible toxin–antitoxin system in Caulobacter crescentus

Gerardo Turcatti, Marc Chambon, Julien Bortoli Chapalay

Bacterial toxin-antitoxin systems (TASs) are thought to respond to various stresses, often inducing growth-arrested (persistent) sub-populations of cells whose housekeeping functions are inhibited. Many such TASs induce this effect through the translation- ...

Nature Publishing Group2016

Translational arrest by a prokaryotic signal recognition particle is mediated by RNA interactions

Henning Paul-Julius Stahlberg

The signal recognition particle (SRP) recognizes signal sequences of nascent polypeptides and targets ribosome-nascent chain complexes to membrane translocation sites. In eukaryotes, translating ribosomes are slowed down by the Alu domain of SRP to allow e ...

Springer Nature2015

PACCMIT/PACCMIT-CDS: identifying microRNA targets in 3′ UTRs and coding sequences

Jiri Vanicek, Ray Marcel Marin Florez, Miroslav Sulc

The purpose of the proposed web server, publicly available at http://paccmit.epfl.ch, is to provide a user-friendly interface to two algorithms for predicting messenger RNA (mRNA) molecules regulated by microRNAs: (i) PACCMIT (Prediction of ACcessible and/ ...

Oxford University Press2015

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ADN antisens

Casein kinase 2 mediated phosphorylation of Spt6 modulates histone dynamics and regulates spurious transcription

The effects of mitochondrial- and histone stress on the C. elegans transcriptome

Structural Features of the Box C/D snoRNP Pre-assembly Process Are Conserved through Species

Hotair Is Dispensible for Mouse Development

Potential Direct Regulators of the Drosophila yellow Gene Identified by Yeast One-Hybrid and RNAi Screens

A Large-Scale Functional Screen to Identify Epigenetic Repressors of Retrotransposon Expression

An experimental evaluation of drug-induced mutational meltdown as an antiviral treatment strategy

Growth control switch by a DNA-damage-inducible toxin–antitoxin system in Caulobacter crescentus

Translational arrest by a prokaryotic signal recognition particle is mediated by RNA interactions

PACCMIT/PACCMIT-CDS: identifying microRNA targets in 3′ UTRs and coding sequences

Graph Chatbot

Chattez avec Graph Search

Hotair Is Dispensible for Mouse Development

Structural Features of the Box C/D snoRNP Pre-assembly Process Are Conserved through Species

Casein kinase 2 mediated phosphorylation of Spt6 modulates histone dynamics and regulates spurious transcription

Potential Direct Regulators of the Drosophila yellow Gene Identified by Yeast One-Hybrid and RNAi Screens

A Large-Scale Functional Screen to Identify Epigenetic Repressors of Retrotransposon Expression

Translational arrest by a prokaryotic signal recognition particle is mediated by RNA interactions

Growth control switch by a DNA-damage-inducible toxin–antitoxin system in Caulobacter crescentus

An experimental evaluation of drug-induced mutational meltdown as an antiviral treatment strategy

PACCMIT/PACCMIT-CDS: identifying microRNA targets in 3′ UTRs and coding sequences

The effects of mitochondrial- and histone stress on the C. elegans transcriptome