Publications associées à Cadre de lecture ouvert

Ribo-DT: An automated pipeline for inferring codon dwell times from ribosome profiling data

Protein synthesis is an energy consuming process characterised as a pivotal and highly regulated step in gene expression. The net protein output is dictated by a combination of translation initiation, elongation and termination rates that have remained dif ...

ACADEMIC PRESS INC ELSEVIER SCIENCE2022

Robust landscapes of ribosome dwell times and aminoacyl-tRNAs in response to nutrient stress in liver

Felix Naef, Cédric Gobet, Frédéric Bruno Martin Gachon, Benjamin Dieter Weger, Nagammal Neelagandan

Translation depends on messenger RNA (mRNA)-specific initiation, elongation, and termination rates. While translation elongation is well studied in bacteria and yeast, less is known in higher eukaryotes. Here we combined ribosome and transfer RNA (tRNA) pr ...

2020

Multilevel regulation of the glass locus during Drosophila eye development

Bart Deplancke, Michael Vincent Frochaux, Abhishek Kumar Mishra

Development of eye tissue is initiated by a conserved set of transcription factors termed retinal determination network (RDN). In the fruit fly Drosophila melanogaster, the zinc-finger transcription factor Glass acts directly downstream of the RDN to contr ...

PUBLIC LIBRARY SCIENCE2019

The fitness landscape of the codon space across environments

Jeffrey David Jensen, Claudia Bank, Sebastian Matuszewski

Fitness landscapes map the relationship between genotypes and fitness. However, most fitness landscape studies ignore the genetic architecture imposed by the codon table and thereby neglect the potential role of synonymous mutations. To quantify the fitnes ...

NATURE PUBLISHING GROUP2018

Role of Cnot6l in maternal mRNA turnover

Radek Jankele

Removal of poly(A) tail is an important mechanism controlling eukaryotic mRNA turnover. The major eukaryotic deadenylase complex CCR4-NOT contains two deadenylase components, CCR4 and CAF1, for which mammalian CCR4 is encoded by Cnot6 or Cnot6l paralogs. W ...

Rockefeller University Press2018

A soft portable wearable pneumatic interactive suit

Jamie Paik, Matthew Aaron Robertson, Harshal Arun Sonar, Sagar Dattatray Joshi, Tigmanshu Bhatnagar

A fully wearable system used for communication and information transfer between two users or between a user and a machine to render an effective and intuitive physical interface for combined input and output functions, the fully wearable system including a ...

2018

Facing The Unknown: Suggesting Alternative Novel Biochemistry in Escherichia coli and Saccharomyces cerevisiae

Vassily Hatzimanikatis, Meriç Ataman, Noushin Hadadi

While advances in genome sequencing have greatly facilitated the inference of metabolic networks, the presence of unknown biochemistry in the organisms still challenges the analysis and understanding of metabolism. Even for one of the most known organism l ...

2017

Olfactory receptor pseudo-pseudogenes

Matteo Dal Peraro, Benoîte Bargeton

Pseudogenes are generally considered to be non-functional DNA sequences that arise through nonsense or frame-shift mutations of protein-coding genes(1). Although certain pseudogene-derived RNAs have regulatory roles(2), and some pseudogene fragments are tr ...

Nature Publishing Group2016

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Cadre de lecture ouvert

Ribo-DT: An automated pipeline for inferring codon dwell times from ribosome profiling data

Wnt5a promotes hippocampal postsynaptic development and GluN2B-induced expression via the eIF2 alpha HRI kinase

Robust landscapes of ribosome dwell times and aminoacyl-tRNAs in response to nutrient stress in liver

Multilevel regulation of the glass locus during Drosophila eye development

The fitness landscape of the codon space across environments

Role of Cnot6l in maternal mRNA turnover

A soft portable wearable pneumatic interactive suit

Rae1/YacP, a new endoribonuclease involved in ribosome-dependent mRNA decay in Bacillus subtilis

Facing The Unknown: Suggesting Alternative Novel Biochemistry in Escherichia coli and Saccharomyces cerevisiae

Olfactory receptor pseudo-pseudogenes

Graph Chatbot

Chattez avec Graph Search

The fitness landscape of the codon space across environments

Multilevel regulation of the glass locus during Drosophila eye development

Role of Cnot6l in maternal mRNA turnover

A soft portable wearable pneumatic interactive suit

Facing The Unknown: Suggesting Alternative Novel Biochemistry in Escherichia coli and Saccharomyces cerevisiae

Robust landscapes of ribosome dwell times and aminoacyl-tRNAs in response to nutrient stress in liver

Ribo-DT: An automated pipeline for inferring codon dwell times from ribosome profiling data

Rae1/YacP, a new endoribonuclease involved in ribosome-dependent mRNA decay in Bacillus subtilis

Wnt5a promotes hippocampal postsynaptic development and GluN2B-induced expression via the eIF2 alpha HRI kinase

Olfactory receptor pseudo-pseudogenes