Concept

Phosphatidylinositol

Publications associées (34)

Evolution of the Hepatic Lipid Profile of the Adult Mouse - in Vivo and in Vitro 1H MRS Assessments at 14.1T

Rolf Gruetter, Hongxia Lei, Ana Francisca Leal Silva Soares

The hepatic lipid content and composition were assessed in healthy mice throughout adulthood. It was found that aging and obesity contributed to increase the amount of lipids in the liver while decreasing the poly-unsaturation degree. The combination of in ...

2013

Proton T(1) relaxation times of metabolites in human occipital white and gray matter at 7 T

Rolf Gruetter, Lijing Xin, Benoît Schaller, Huanxiang Lu

Proton T(1) relaxation times of metabolites in the human brain have not previously been published at 7 T. In this study, T(1) values of CH(3) and CH(2) group of N-acetylaspartate and total creatine as well as nine other brain metabolites were measured in o ...

Wiley-Blackwell2013

Phosphoinositides in Golgi Complex Function

The Golgi complex is a ribbon-like organelle composed of stacks of flat cisternae interconnected by tubular junctions. It occupies a central position in the endomembrane system as proteins and lipids that are synthesized in the endoplasmic reticulum (ER) p ...

2012

Distinct Spatial and Molecular Features of Notch Pathway Assembly in Regulatory T Cells

Freddy Radtke

Variations in the spatial localization of signaling components and crosstalk among signaling cascades are mechanisms through which diversity in signaling networks is generated. The receptor Notch provides an example of regulation by spatial localization: I ...

2012

Characterization of supported lipid bilayers incorporating the phosphoinositides phosphatidylinositol 4,5-biphosphate and phosphoinositol-3,4,5-triphosphate by complementary techniques

Esther Amstad

Phosphoinositides are involved in a large number of processes in cells and it is very demanding to study individual protein-lipid interactions in vivo due to their rapid turnover and involvement in simultaneous events. Supported lipid bilayers (SLBs) conta ...

American Vacuum Society2010

Formation and study of single metal ion–phospholipid complexes in biphasic electrospray ionization mass spectrometry

Hubert Girault, Daniel Filipe Dos Santos Alves Jana, Manuel Alejandro Méndez Agudelo, Michel Prudent

Single metal ion-phospholipid complexes are observed in biphasic electrospray ionization mass spectrometry (BESI-MS) using a dual-channel microsprayer. Such a microsprayer makes it possible to put into contact two immiscible liquids within the Taylor cone. ...

Royal Society of Chemistry2010

The multiple roles of PtdIns(4)P - not just the precursor of PtdIns(4,5)P2

Giovanni D'Angelo

The phosphoinositides (PIs) are membrane phospholipids that actively operate at membrane-cytosol interfaces through the recruitment of a number of effector proteins. In this context, each of the seven different PI species represents a topological determina ...

2008

Putative role of CG3160 in morphogen secretion

Gilles Udin

Morphogens are secreted molecules that influence the fate of neighboring cells in a concentration-dependant manner. For this reason, their distribution and diffusion strongly influence their roles. In my master thesis, I focused on a posttranslational modi ...

2008

Time-resolved luminescence microscopy of bimetallic lanthanide helicates in living cells

Jean-Claude Bünzli, Anne-Sophie Chauvin, Caroline Vandevyver, Bo Song

The cellular uptake mechanism and intracellular distribution of emissive lanthanide helicates have been elucidated by time-resolved luminescence microscopy (TRLM). The helicates are non-cytotoxic and taken up by normal (HaCat) and cancer (HeLa, MCF-7) cell ...

2008

Hrs and SNX3 functions in sorting and membrane invagination within multivesicular bodies

Françoise Gisou van der Goot Grunberg, Laurence Gouzi Abrami

After internalization, ubiquitinated signaling receptors are delivered to early endosomes. There, they are sorted and incorporated into the intralumenal invaginations of nascent multivesicular bodies, which function as transport intermediates to late endos ...

2008

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