Concept

Vertèbre cervicale

Publications associées (33)

Additive and global functions of HoxA cluster genes in mesoderm derivatives

Hox genes encode transcription factors that play a central role in the specification of regional identities along the anterior to posterior body axis. In the developing mouse embryo, Hox genes from all four genomic clusters are involved in range of develop ...

Elsevier2010

Geometry- and load-specific optimization of the collagen network's fibre orientation in the lumbar spine's annulus fibrosus

Andreas Schmocker

In Europe, low back pain (LBP) affects the quality of life of up to 30% of the active population. Although the origin of LBP is not well identified and is probably not unique, epidemiological studies suggest that the severity of the disease is correlated w ...

2010

Changes in Hox genes' structure and function during the evolution of the squamate body plan

Denis Duboule

Hox genes are central to the specification of structures along the anterior-posterior body axis, and modifications in their expression have paralleled the emergence of diversity in vertebrate body plans. Here we describe the genomic organization of Hox clu ...

Nature Publishing Group2010

Recombinant adeno-associated virus serotype 6 (rAAV2/6)-mediated gene transfer to nociceptive neurons through different routes of delivery

Patrick Aebischer, Christopher Towne

BACKGROUND: Gene transfer to nociceptive neurons of the dorsal root ganglia (DRG) is a promising approach to dissect mechanisms of pain in rodents and is a potential therapeutic strategy for the treatment of persistent pain disorders such as neuropathic pa ...

2009

Scanning and transmission electron microscopy for evaluation of order/disorder in bone structure

Philippe Buffat, Elena Suvorova Buffat

A comparative characterization of the structure of normal and abnormal (osteoporotic) human lumbar and thoracic vertebrae samples was carried out to reveal the type of possible disorder. Samples from the bone fragments extracted during the surgery due to v ...

2007

Analysis of the stability of a posterior fusion system for the treatment of burst fractures

Dominique Pioletti, Arne Christian Vogel, Martin Aeberhard

In the framework of spine traumatology, burst fractures are severe and are often caused by car accidents or by falls. The vertebra breaks under the traumatic compression and pieces of it are shattered in all directions. This type of fracture is often treat ...

2007

Hox gene function in vertebrate gut morphogenesis: the case of the caecum

Denis Duboule, Jozsef Zakany

The digestive tract is made of different subdivisions with various functions. During embryonic development, the developing intestine expresses combinations of Hox genes along its anterior to posterior axis, suggesting a role for these genes in this regiona ...

2007

Head-tail patterning of the vertebrate embryo: one, two or many unresolved problems?

Denis Duboule

When, where and how is the head-tail axis of the embryo set up during development? These are such fundamental and intensely studied questions that one might expect them to have been answered long ago. Not so; we still understand very little about the cellu ...

2006

Requirement for beta-catenin in anterior-posterior axis formation in mice

The anterior-posterior axis of the mouse embryo is defined before formation of the primitive streak, and axis specification and subsequent anterior development involves signaling from both embryonic ectoderm and visceral endoderm. Tauhe Wnt signaling pathw ...

2000

Wall stresses in the carotid bifurcation: Effects of wall non-homogeneity and correlation with intimal thickness

Nikolaos Stergiopoulos, Jean-Jacques Meister

A finite element model of the human carotid bifurcation was developed to investigate the possibility that pressure-induced arterial wall stresses lead to the formation of atherosclerosis. The effect of material non-homogeneity was investigated by measuring ...

1998

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