Publications associées à Pharmacovigilance

From aseismic to seismic slip during fluid pressure oscillations on laboratory fault

Marie Estelle Solange Violay, François Xavier Thibault Passelègue, Carolina Giorgetti, Corentin Jean-Marie Rémi Noël

A rise in fluid pressure decreases the effective normal stress acting on faults, facilitating reactivation. Within the upper crust, fluid pressure cyclic perturbations are common. They can originate from natural causes such as oceanic tides, seasonal hydro ...

2019

Heart rate variability at bedtime predicts subsequent sleep features

Fiorenzo Artoni, Maria Paola Tramonti Fantozzi

Getting enough sleep during the night is important for preventing adverse short- and long-term health outcomes. The sympathetic-parasympathetic autonomic balance, characteristics of the pre-bed time resting period, correlates with sleep efficiency. We inve ...

IEEE2019

Stress Impacts the Regulation Neuropeptides in the Rat Hippocampus and Prefrontal Cortex

Gregor Rainer, Laura Lozano Montes, Nan Zhao

Adverse life experience increases the lifetime risk to several stress-related psychopathologies, such as anxiety or depressive–like symptom following stress in adulthood. However, the neurochemical modulations triggered by stress have not been fully charac ...

2018

Improving Efficacy and Safety of Agonistic Anti-CD40 Antibody Through Extracellular Matrix Affinity

Jeffrey Alan Hubbell, Melody Swartz, Lambert Charles François Potin, Martina Damo, Jun Ishihara, Kazuto Fukunaga

CD40 is an immune costimulatory receptor expressed by antigen-presenting cells. Agonistic anti-CD40 antibodies have demonstrated considerable antitumor effects yet can also elicit serious treatment-related adverse events, such as liver toxicity, including ...

AMER ASSOC CANCER RESEARCH2018

The FDA-approved natural product dihydroergocristine reduces the production of the Alzheimer's disease amyloid-beta peptides

Patrick Fraering, Jianhua Liu, Jing Yu

Known gamma-secretase inhibitors or modulators display an undesirable pharmacokinetic profile and toxicity and have therefore not been successful in clinical trials for Alzheimer's disease (AD). So far, no compounds from natural products have been identifi ...

Nature Publishing Group2015

A review of the fate of micropollutants in wastewater treatment plants

David Andrew Barry, Christof Holliger, Luca Rossi, Jonas Margot

Municipal wastewaters are contaminated by a wide range of chemicals, from surfactants to heavy metals, including pharmaceutical residues, personal care products, various household chemicals, and biocides/pesticides. Their release into the environment, wher ...

Wiley-Blackwell2015

Influence of chemically p-type doped active organic semiconductor on the film thickness versus performance trend in cyanine/C-60 bilayer solar cells

Roland Hany, Jakob Heier, Adriana Paracchino, Beat Ruhstaller, Thomas Geiger

Simple bilayer organic solar cells rely on very thin coated films that allow for effective light absorption and charge carrier transport away from the heterojunction at the same time. However, thin films are difficult to coat on rough substrates or over la ...

Iop Publishing Ltd2015

Effects of adverse early-life events on aggression and anti-social behaviours in animals and humans

Maria del Carmen Sandi Perez

We review here the impact of early adversities on the development of violence and antisocial behaviour in humans, and present three etiological animal models of escalated rodent aggression, each disentangling the consequences of one particular adverse earl ...

Wiley-Blackwell2014

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Pharmacovigilance

From aseismic to seismic slip during fluid pressure oscillations on laboratory fault

Heart rate variability at bedtime predicts subsequent sleep features

Stress Impacts the Regulation Neuropeptides in the Rat Hippocampus and Prefrontal Cortex

Improving Efficacy and Safety of Agonistic Anti-CD40 Antibody Through Extracellular Matrix Affinity

Low intensity transcranial electric stimulation: Safety, ethical, legal regulatory and application guidelines

Identifying Adverse Effects of HIV Drug Treatment and Associated Sentiments Using Twitter

The FDA-approved natural product dihydroergocristine reduces the production of the Alzheimer's disease amyloid-beta peptides

A review of the fate of micropollutants in wastewater treatment plants

Influence of chemically p-type doped active organic semiconductor on the film thickness versus performance trend in cyanine/C-60 bilayer solar cells

Effects of adverse early-life events on aggression and anti-social behaviours in animals and humans

Graph Chatbot

Chattez avec Graph Search

Heart rate variability at bedtime predicts subsequent sleep features

Stress Impacts the Regulation Neuropeptides in the Rat Hippocampus and Prefrontal Cortex

Improving Efficacy and Safety of Agonistic Anti-CD40 Antibody Through Extracellular Matrix Affinity

Identifying Adverse Effects of HIV Drug Treatment and Associated Sentiments Using Twitter

A review of the fate of micropollutants in wastewater treatment plants

The FDA-approved natural product dihydroergocristine reduces the production of the Alzheimer's disease amyloid-beta peptides

Low intensity transcranial electric stimulation: Safety, ethical, legal regulatory and application guidelines

Influence of chemically p-type doped active organic semiconductor on the film thickness versus performance trend in cyanine/C-60 bilayer solar cells

Effects of adverse early-life events on aggression and anti-social behaviours in animals and humans

From aseismic to seismic slip during fluid pressure oscillations on laboratory fault