Publications associées à Astrogliosis

Metabolic gene expression changes in astrocytes in Multiple Sclerosis cerebral cortex are indicative of immune-mediated signaling

Pierre Magistretti, Igor Allaman

Emerging as an important correlate of neurological dysfunction in Multiple Sclerosis (MS), extended focal and diffuse gray matter abnormalities have been found and linked to clinical manifestations such as seizures, fatigue and cognitive dysfunction. To in ...

Elsevier2015

Marinesco-Sjogren syndrome protein SIL1 regulates motor neuron subtype-selective ER stress in ALS

Bernard Schneider, Céline Ruegsegger, Niran Maharjan

Mechanisms underlying motor neuron subtype selective endoplasmic reticulum (ER) stress and associated axonal pathology in amyotrophic lateral sclerosis (ALS) remain unclear. Here we show that the molecular environment of the ER between motor neuron subtype ...

Nature Publishing Group2015

Quantitative Analysis of Myelin and Axonal Remodeling in the Uninjured Motor Network After Stroke

Jean-Philippe Thiran, Reto Meuli, Alessandro Daducci, Cristina Granziera, Djalel Eddine Meskaldji, Gunnar Krüger, Gloria Menegaz

Objectives: Contralesional brain connectivity plasticity was previously reported after stroke. This study aims at disentangling the biological mechanisms underlying connectivity plasticity in the uninjured motor network after an ischemic lesion. In particu ...

2015

Control of Mitochondrial pH by Uncoupling Protein 4 in Astrocytes Promotes Neuronal Survival

Pierre Magistretti, Hélène Danielle Perreten Lambert, Sylvain Eric Lengacher, Manuel Raphael Zenger, Jean-Yves Chatton

Brain activity is energetically costly and requires a steady and highly regulated flow of energy equivalents between neural cells. It is believed that a substantial share of cerebral glucose, the major source of energy of the brain, will preferentially be ...

American Society for Biochemistry and Molecular Biology2014

In vivo quantification of neuro-glial metabolism and glial glutamate concentration using 1H-[13C] MRS at 14.1T

Rolf Gruetter, Lijing Xin, Bernard Lanz

Astrocytes have recently become a major center of interest in neurochemistry with the discoveries on their major role in brain energy metabolism. An interesting way to probe this glial contribution is given by in vivo 13C NMR spectroscopy coupled with the ...

Wiley-Blackwell2014

Extracellular matrix components in peripheral nerve repair: how to affect neural cellular response and nerve regeneration?

Stéphanie Lacour, Alba Carla De Luca

Peripheral nerve injury is a serious problem affecting significantly patients' life. Autografts are the "gold standard" used to repair the injury gap, however, only 50% of patients fully recover from the trauma. Artificial conduits are a valid alternative ...

Shenyang Editorial Dept Neural Regeneration Res2014

Regulation of Neurotrophic Factors and Energy Metabolism by Antidepressants in Astrocytes

Pierre Magistretti, Jean-Luc Martin, Igor Allaman

There is growing evidence that astrocytes are involved in the neuropathology of major depression. In particular, decreases in glial cell density observed in the cerebral cortex of individuals with major depressive disorder are accompanied by a reduction of ...

Bentham Science Publishers2013

Astrocyte–neuron co-culture on microchips based on the model of SOD mutation to mimic ALS

Philippe Renaud, Pierre Magistretti, Patrick Aebischer, Sylvain Eric Lengacher, Anja Kunze, Elisabeth Anne Dirren

Amyotrophic lateral sclerosis (ALS) is the most common motor neuron disease. ALS is believed to be a non-cell autonomous condition, as other cell types, including astrocytes, have been implicated in disease pathogenesis. Hence, to facilitate the developmen ...

Royal Soc Chemistry2013

BMP signaling specifies the development of a large and fast CNS synapse

Graham Knott, Ralf Schneggenburger, Enida Gjoni, Elin Kristina Kronander, Le Xiao

excitatory synapses with multiple active zones ensure reliable and fast information transfer at specific points in neuronal circuits. However, the mechanisms that determine synapse size in CNS circuits are largely unknown. Here we use the calyx of Held syn ...

Nature Publishing Group2013

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Astrogliosis

Metabolic gene expression changes in astrocytes in Multiple Sclerosis cerebral cortex are indicative of immune-mediated signaling

Marinesco-Sjogren syndrome protein SIL1 regulates motor neuron subtype-selective ER stress in ALS

Quantitative Analysis of Myelin and Axonal Remodeling in the Uninjured Motor Network After Stroke

Control of Mitochondrial pH by Uncoupling Protein 4 in Astrocytes Promotes Neuronal Survival

In vivo quantification of neuro-glial metabolism and glial glutamate concentration using 1H-[13C] MRS at 14.1T

Corticospinal neuroprostheses to restore locomotion after spinal cord injury

Extracellular matrix components in peripheral nerve repair: how to affect neural cellular response and nerve regeneration?

Regulation of Neurotrophic Factors and Energy Metabolism by Antidepressants in Astrocytes

Astrocyte–neuron co-culture on microchips based on the model of SOD mutation to mimic ALS

BMP signaling specifies the development of a large and fast CNS synapse

Graph Chatbot

Chattez avec Graph Search

Metabolic gene expression changes in astrocytes in Multiple Sclerosis cerebral cortex are indicative of immune-mediated signaling

Control of Mitochondrial pH by Uncoupling Protein 4 in Astrocytes Promotes Neuronal Survival

Marinesco-Sjogren syndrome protein SIL1 regulates motor neuron subtype-selective ER stress in ALS

Corticospinal neuroprostheses to restore locomotion after spinal cord injury

Quantitative Analysis of Myelin and Axonal Remodeling in the Uninjured Motor Network After Stroke

In vivo quantification of neuro-glial metabolism and glial glutamate concentration using 1H-[13C] MRS at 14.1T

Extracellular matrix components in peripheral nerve repair: how to affect neural cellular response and nerve regeneration?

Astrocyte–neuron co-culture on microchips based on the model of SOD mutation to mimic ALS

BMP signaling specifies the development of a large and fast CNS synapse

Regulation of Neurotrophic Factors and Energy Metabolism by Antidepressants in Astrocytes