Concept
Facteur anti-hémophilique B
Publications associées (31)
Nonlocal effects in negative triangularity TCV plasmas
Olivier Sauter, Stefano Coda, Laurent Villard, Stephan Brunner, Zhouji Huang, Gabriele Merlo, Claudio Marini
Global gradient driven gyrokinetic simulations performed with the Gyrokinetic Electromagnetic Numerical Experiment (GENE) code are used to investigate Tokamak a configuration variable (TCV) plasmas with negative triangularity. Considering limited L-mode pl ...
IOP PUBLISHING LTD2021De novo development of proteolytically resistant therapeutic peptides for oral administration
Christian Heinis, Luciano Andres Abriata, Florence Pojer, Xudong Kong, Vanessa Carle, Jun Moriya
The oral administration of peptide drugs is hampered by their metabolic instability and limited intestinal uptake. Here, we describe a method for the generation of small target-specific peptides (less than 1,600 Da in size) that resist gastrointestinal pro ...
2020Tissue Factor-Independent Coagulation Correlates with Clinical Phenotype in Factor XI Deficiency and Replacement Therapy
Christian Heinis, Vanessa Carle, Alessandro Aliotta
Background In factor XI (FXI) deficiency, bleeding cannot be predicted by routine analyses. Since FXI is involved in tissue factor (TF)-independent propagation loop of coagulation, we hypothesized that investigating the spatiotemporal separated phases of c ...
GEORG THIEME VERLAG KG2020FasR Regulates Fatty Acid Biosynthesis and Is Essential for Virulence of Mycobacterium tuberculosis
Mycobacterium tuberculosis, the etiologic agent of human tuberculosis, is the world's leading cause of death from an infectious disease. One of the main features of this pathogen is the complex and dynamic lipid composition of the cell envelope, which adap ...
FRONTIERS MEDIA SA2020Re-evaluating natural resource investments under uncertainty: An alternative to limited traditional approaches
The need to evaluate natural resource investments under uncertainty has given rise to the development of real options valuation; however, the analysis of such investments has been restricted by the capabilities of existing valuation approaches. We re-visit ...
2020Data-driven Measurement Designs for Magnetic Resonance Imaging
Despite being a powerful medical imaging technique which does not emit any ionizing radiation, magnetic resonance imaging (MRI) always had the major problem of long scanning times that can take up to an hour depending on the application. It also requires u ...
EPFL2019