Publications associées à Protéine G

Selective Localization of Hierarchically Assembled Particles to Plasma Membranes of Living Cells

Francesco Stellacci, Randy Patrick Carney

Particles that preferentially partition to a specific cellular subunit, such as the nucleus, mitochondria, or the cytoskeleton, are of relevance to a number of applications, including drug delivery, genetic manipulation, or self-assembly. Here, hierarchica ...

WILEY-V C H VERLAG GMBH2019

Microfluidic protein isolation and sample preparation for high-resolution cryo-EM

Henning Paul-Julius Stahlberg, Inayathulla Mohammed

High-resolution structural information is essential to understand protein function. Protein-structure determination needs a considerable amount of protein, which can be challenging to produce, often involving harsh and lengthy procedures. In contrast, the ...

Proceedings of the National Academy of Sciences2019

Structure of the mitochondrial import gate reveals distinct preprotein paths

Marilena Wischnewski, Jian Qiu, Thomas Becker

The translocase of the outer mitochondrial membrane (TOM) is the main entry gate for proteins(1-4). Here we use cryo-electron microscopy to report the structure of the yeast TOM core complex(5-9) at 3.8-angstrom resolution. The structure reveals the high-r ...

2019

New Binding Sites, New Opportunities for GPCR Drug Discovery

Horst Vogel, Thamani Dahoun, Shuguang Yuan, Yen-Huan Li

Many central biological events rely on protein-ligand interactions. The identification and characterization of protein-binding sites for ligands are crucial for the understanding of functions of both endogenous ligands and synthetic drug molecules. G prote ...

ELSEVIER SCIENCE LONDON2019

Diverse roles of TssA-like proteins in the assembly of bacterial type VI secretion systems

Henning Paul-Julius Stahlberg, Sergey Nazarov

Protein translocation by the bacterial type VI secretion system (T6SS) is driven by a rapid contraction of a sheath assembled around a tube with associated effectors. Here, we show that TssA-like or TagA-like proteins with a conserved N-terminal domain and ...

WILEY2019

Dynamics of protein synthesis and degradation through the cell cycle

David Michael Suter, Andrea Brigitta Alber

Protein expression levels depend on the balance between their synthesis and degradation rates. Even quiescent (G(0)) cells display a continuous turnover of proteins, despite protein levels remaining largely constant over time. In cycling cells, global prot ...

TAYLOR & FRANCIS INC2019

Polymer brush interfaces for protein biosensing prepared by surface-initiated controlled radical polymerization

Harm-Anton Klok, Mark Billing, Michael Badoux

Thin polymer films that are able to bind proteins are of great relevance for a wide variety of biosensor and biochip applications. Some of these applications require films that have high protein binding capacities while others call for surfaces that allow ...

2019

Identifying the role of complex I in organohalide respiration of Firmicutes

Christof Holliger, Julien Maillard, Romain Hamelin, Mathilde Stéphanie Willemin

Organohalide-respiring bacteria (OHRB) are capable to link energy conservation with the use of organohalide compounds as terminal electron acceptors. While obligate OHRB relies only on this process for growing, facultative OHRB are able to use alternative ...

2018

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Protéine G

A ligand-based system for receptor-specific delivery of proteins

Selective Localization of Hierarchically Assembled Particles to Plasma Membranes of Living Cells

Microfluidic protein isolation and sample preparation for high-resolution cryo-EM

Structure of the mitochondrial import gate reveals distinct preprotein paths

New Binding Sites, New Opportunities for GPCR Drug Discovery

Chemical and biophysical methods to explore dynamic mechanisms of chromatin silencing

Diverse roles of TssA-like proteins in the assembly of bacterial type VI secretion systems

Dynamics of protein synthesis and degradation through the cell cycle

Polymer brush interfaces for protein biosensing prepared by surface-initiated controlled radical polymerization

Identifying the role of complex I in organohalide respiration of Firmicutes

Graph Chatbot

Chattez avec Graph Search

Dynamics of protein synthesis and degradation through the cell cycle

Chemical and biophysical methods to explore dynamic mechanisms of chromatin silencing

New Binding Sites, New Opportunities for GPCR Drug Discovery

Polymer brush interfaces for protein biosensing prepared by surface-initiated controlled radical polymerization

Diverse roles of TssA-like proteins in the assembly of bacterial type VI secretion systems

Selective Localization of Hierarchically Assembled Particles to Plasma Membranes of Living Cells

Identifying the role of complex I in organohalide respiration of Firmicutes

A ligand-based system for receptor-specific delivery of proteins

Microfluidic protein isolation and sample preparation for high-resolution cryo-EM

Structure of the mitochondrial import gate reveals distinct preprotein paths