Concept

Fasciola hepatica

Publications associées (10)

Modelled effects of prawn aquaculture on poverty alleviation and schistosomiasis control

Andrea Rinaldo, Lorenzo Mari, Francisco Javier Perez Saez, Marino Gatto

Recent evidence suggests that snail predators may aid efforts to control the human parasitic disease schistosomiasis by eating aquatic snail species that serve as intermediate hosts of the parasite. Here, potential synergies between schistosomiasis control ...

NATURE PUBLISHING GROUP2019

Empirical Characterization of Particle Size Distribution Spatial Dynamics for Helminth Eggs Detection in Waste Stabilization Ponds (WSP)

Paolo Perona

This study assesses seasonal particle size distribution (PSD) dynamics inside a waste stabilization ponds (WSP) (Buguruni, Tanzania) to understand settling dynamics of wastewater particles with an interest in helminth eggs. Results indicate that particles ...

2018

Enteric helminth-induced type I interferon signaling protects against pulmonary virus infection through interaction with the microbiota

Eva Sabrina Gollwitzer, Nicola Harris, Benjamin John Marsland

BACKGROUND: Helminth parasites have been reported to have beneficial immunomodulatory effects in patients with allergic and autoimmune conditions and detrimental consequences in patients with tuberculosis and some viral infections. Their role in coinfectio ...

Elsevier2017

Open Source Drug Discovery: Highly Potent Antimalarial Compounds Derived from the Tres Cantos Arylpyrroles

Luc Patiny, Anna Lee, Eileen Ryan

The development of new antimalarial compounds remains a pivotal part of the strategy for malaria elimination. Recent large-scale phenotypic screens have provided a wealth of potential starting points for hit-to-lead campaigns. One such public set is explor ...

Amer Chemical Soc2016

Modeling the spatial distribution of Theileria parva (Theiler 1904), causative agent of East Coast Fever disease in cattle

Stéphane Joost, Sylvie Stucki, Elia Vajana, Pierre Taberlet

Theileria parva is a protozoan emo-parasite affecting sub-Saharan Bos taurus and Bos indicus populations. It is the causative agent of East Coast Fever, a major cattle disease causing the death of ~1.1∙106 animals per year and an annual loss of ~168∙106 US ...

2015

Signalling in malaria parasites. The MALSIG consortium.

Ashish Sharma

Depending on their developmental stage in the life cycle, malaria parasites develop within or outside host cells, and in extremely diverse contexts such as the vertebrate liver and blood circulation, or the insect midgut and hemocoel. Cellular and molecula ...

2009

Invasive and indigenous microbiota impact intestinal stem cell activity through multiple pathways in Drosophila

Bruno Lemaitre, Nichole Broderick, Sveta Chakrabarti

Gut homeostasis is controlled by both immune and developmental mechanisms, and its disruption can lead to inflammatory disorders or cancerous lesions of the intestine. While the impact of bacteria on the mucosal immune system is beginning to be precisely u ...

2009

The host defense of Drosophila melanogaster

Bruno Lemaitre

To combat infection, the fruit fly Drosophila melanogaster relies on multiple innate defense reactions, many of which are shared with higher organisms. These reactions include the use of physical barriers together with local and systemic immune responses. ...

Annual Reviews2007

Zebrafish Angiotensin II Receptor-like 1a (agtrl1a) is expressed in migrating hypoblast, vasculature, and in multiple embryonic epithelia

Andrew Charles Oates

The human gene AGTRL1 is an angiotensin II receptor-like gene expressed in vasculature, which acts as the receptor for the small peptide APELIN, and a co-receptor for Human Immunodeficiency Virus. Mammalian AGTRL1 has been shown to modulate cardiac contrac ...

2007

Development of Antimalaria Immunity in Mice Lacking Ifn-Gamma Receptor

Michel Aguet

IFN-gamma receptor deficient (IFN-gamma R(-/-)) mice, immunized with different developmental stages of malaria parasites, were used to define the mechanisms of protection against the various stages of this infection. IFN-gamma R(-/-) mice fail to develop p ...

1995

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