Chimeric antigen receptor (CAR) T cells in the solid tumor microenvironment enter a partially dysfunctional state called T cell exhaustion. Interleukin (IL)-10-producing CAR T cells retain their metabolic fitness, resist T cell exhaustion and display unpre ...
Mobility scholars have long been interested in challenging the automobile's hegemony in the street, particularly by highlighting how to develop urban cycling. The article contributes to this task by explaining how one type of conflict between the bike and ...
The use of CAR technologies has revolutionized cancer treatment. Their unprecedented efficacy against B cell malignancies has opened the doors for a lot of excitement and research in the field. These synthetic receptors are composed of an antigen recogniti ...
Car sharing systems (CSSs) are one of the environmentally beneficial solutions in urban transportation. However, the operators still struggle to make these systems profitable. One of the main contributors in operational cost is rebalancing operations. Ther ...
Chimeric antigen receptors (CARs) are synthetic, transmembrane proteins that trigger immune cell signaling following their engagement. They have been first utilized in T cells and later in natural killer (NK) cells to redirect their cytotoxicity toward a s ...
Microscopic traffic flow models can be distinguished in lane-based or lane-free depending on the degree of lane-discipline. This distinction holds true only if motorcycles are neglected in lane-based traffic. In cities, as opposed to highways, this is an o ...
Encouraging a modal shift from individual transportation to less polluting modes such as public transport, walking and cycling, is now a key recommendation of the UN to reach the goals set by the Paris Agreement. Achieving this ambitious goal requires a de ...
Cars are some of the most security-critical consumer devices. On the one hand, owners expect rich infotainment features, including audio, hands-free calls, contact management, or navigation through their connected mobile phone. On the other hand, the infot ...
Vehicle sharing systems (VSSs) allow users to rent vehicles for a short period of time, in a more flexible and convenient manner compared to the traditional vehicle rental services. The long-term VSS subscription replaces the need for contract signing for ...
The new era of shared economy has raised our expectations to make mobility more sustainable through better utilization of existing resources and capacity. In this thesis, we focus on the design of transport systems that stimulate multi-purpose trips with t ...
