Publications associées à Membrane basale

Mechanical Properties of Soft Biological Membranes for Organ-on-a-Chip Assessed by Bulge Test and AFM

Georg Fantner, Johann Michler, Veronika Cencen

Advanced in vitro models called “organ-on-a-chip” can mimic the specific cellular environment found in various tissues. Many of these models include a thin, sometimes flexible, membrane aimed at mimicking the extracellular matrix (ECM) scaffold of in vivo ...

2021

The secreted protease Adamts18 links hormone action to activation of the mammary stem cell niche

Cathrin Brisken, Giovanna Ambrosini, Marian Caikovski, Dalya Ataca, Philipp Bucher, Renuga Devi Rajaram, Patrik Aouad, Marie Shamseddin, Céline Berthe Constantin, Csaba Ferenc László

Estrogens and progesterone control breast development and carcinogenesis via their cognate receptors expressed in a subset of luminal cells in the mammary epithelium. How they control the extracellular matrix, important to breast physiology and tumorigenes ...

Nature Research2020

90 YEARS OF PROGESTERONE Progesterone receptor signaling in the normal breast and its implications for cancer

Cathrin Brisken, Valentina Scabia

Progesterone is considered as the pregnancy hormone and acts on many different target tissues. Progesterone receptor (PR) signaling is important for normal development and the physiologic function of the breast and impinges on breast carcinogenesis. Both s ...

BIOSCIENTIFICA LTD2020

Improving a fish intestinal barrier model by combining two rainbow trout cell lines: epithelial RTgutGC and fibroblastic RTgutF

Philippe Renaud, Kristin Schirmer, Carolin Drieschner, Hannah Inka Schug

An in vitro model of the fish intestine is of interest for research and application in diverse fields such as fish physiology, aquaculture and chemical risk assessment. The recently developed epithelial barrier model of the fish intestine relies on the RTg ...

Springer2019

Adamts18 Function in Mammary Gland Development

Dalya Ataca

Ovarian hormones control mammary gland development and impinge on breast carcinogenesis acting via their cognate receptors in the luminal epithelium. The extracellular matrix has a key role in physiology and disease but how the two are linked is poorly und ...

EPFL2019

Surface-confined Electrochemiluminescence Microscopy of Cell Membranes

Andreas Stephan Lesch, Milica Jovic

Herein is reported a surface-confined microscopy based on electrochemiluminescence (ECL) which allows to image the plasma membrane of single cells at the interface with an electrode. By analyzing photoluminescence (PL), ECL and AFM images of mammalian CHO ...

2018

Deciphering the subcapsular epithelial cells in human fetal and postnatal thymus

Diane Sophie Elodie Hemon

Most papers related to thymus focus on the cortical and medullary epithelial cells whereas the subcapsular layer is ignored. In this thesis, we are providing new informations about the subcapsular thymic epithelial cells (TECs) by comparing them to cortica ...

EPFL2017

Miniaturized Dielectric Elastomer Actuator for Mechanical Stimulation of Monolayer Cell Cultures

Alexandre Poulin

This thesis advances the field of dielectric elastomer actuators (DEAs) through the development of device designs, fabrication processes, strain characterization technique and modelling tool. It provides the first demonstration that DEAs can be interfaced ...

EPFL2016

Long-term Intravital Immunofluorescence Imaging of Tissue Matrix Components with Epifluorescence and Two-photon Microscopy

Melody Swartz, Witold Waldemar Kilarski, Amanda Waite Lund, Manuel Andreas Fankhauser

Besides being a physical scaffold to maintain tissue morphology, the extracellular matrix (ECM) is actively involved in regulating cell and tissue function during development and organ homeostasis. It does so by acting via biochemical, biomechanical, and b ...

Journal Of Visualized Experiments2014

A role for angiopoietin-2 in organ-specific metastasis

Michele De Palma, Nicolo Rigamonti

Angiopoietin-2 (ANG2/ANGPT2) has recently emerged as a promising target for the inhibition of tumor metastasis. In this issue of Cell Reports, Minami et al. show that the calcineurin-NFAT pathway promotes pulmonary tumor metastasis by inducing ANG2 in the ...

Elsevier2013